Design of a facility for boron neutron capture therapy, by MCNP, in a fast reactor

被引:0
|
作者
Casali, F [1 ]
Agosteo, S [1 ]
Alfinito, M [1 ]
Burn, KW [1 ]
Chirco, P [1 ]
Nava, E [1 ]
Rosi, G [1 ]
Rossi, M [1 ]
Zanarini, M [1 ]
机构
[1] Univ Bologna, Dept Phys, I-40126 Bologna, Italy
关键词
D O I
暂无
中图分类号
TL [原子能技术]; O571 [原子核物理学];
学科分类号
0827 ; 082701 ;
摘要
Boron Neutron Capture Therapy (BNCT) is a highly selective technique for the treatment of localised infiltrating cancers, such as gliomas in the human brain. The treatment can be optimised by operating on two independent parameters: the boron selective concentration in tumor cells and the neutron capture rate. Neutron sources providing an epithermal spectrum are being considered for clinical use, because thermal neutrons have a poor penetration power and cannot be used for the treatment of deeply located tumors. In this work, the design of an epithermal beam for BNCT at the low-power fast-flux reactor TAPIRO in Rome is presented.
引用
收藏
页码:1688 / 1692
页数:5
相关论文
共 50 条
  • [41] Feasibility of boron neutron capture enhancement of fast neutron therapy utilizing a superconducting cyclotron
    Maughan, RL
    Kota, C
    Forman, JD
    [J]. ADVANCES IN NEUTRON CAPTURE THERAPY, VOLS I AND II: VOL I: MEDICINE AND PHYSICS, VOL II: CHEMISTRY AND BIOLOGY, 1997, 1132 : A490 - A495
  • [42] Strategic Clinical Trial Design for Boron Neutron Capture Therapy
    Wittig, Andrea
    Sauerwein, Wolfgang A. G.
    [J]. CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS, 2023, 38 (03) : 195 - 200
  • [43] The upgrade of the heavy water facility of the Kyoto University Reactor for neutron capture therapy
    Kobayashi, T
    Kanda, K
    Fujita, Y
    Sakurai, Y
    Ono, K
    [J]. ADVANCES IN NEUTRON CAPTURE THERAPY, VOLS I AND II: VOL I: MEDICINE AND PHYSICS, VOL II: CHEMISTRY AND BIOLOGY, 1997, 1132 : A321 - A325
  • [44] EPITHERMAL NEUTRON BEAM DESIGN FOR NEUTRON-CAPTURE THERAPY AT THE POWER BURST FACILITY AND THE BROOKHAVEN MEDICAL-RESEARCH REACTOR
    WHEELER, FJ
    PARSONS, DK
    RUSHTON, BL
    NIGG, DW
    [J]. NUCLEAR TECHNOLOGY, 1990, 92 (01) : 106 - 117
  • [45] Boron neutron capture enhancement of fast neutron radiotherapy
    Stelzer, KJ
    Laramore, GE
    Risler, R
    Wiens, L
    Griffin, TW
    [J]. APPLICATION OF ACCELERATORS IN RESEARCH AND INDUSTRY - PROCEEDINGS OF THE FOURTEENTH INTERNATIONAL CONFERENCE, PTS 1 AND 2, 1997, (392): : 1277 - 1279
  • [46] Toward a final design for the Birmingham boron neutron capture therapy neutron beam
    Allen, DA
    Beynon, TD
    Green, S
    James, ND
    [J]. MEDICAL PHYSICS, 1999, 26 (01) : 77 - 82
  • [47] DOSE ASSESSMENT WITH MCNP5/X CODE FOR BORON NEUTRON CAPTURE THERAPY OF PANCREAS CANCER
    Krsti, Dragana Z.
    Nikezi, Dragoslav R.
    Zivkovi, Milena P.
    Jeremi, Marija Z.
    [J]. NUCLEAR TECHNOLOGY & RADIATION PROTECTION, 2021, 36 (03): : 294 - 298
  • [48] Neutron capture autoradiography for a study on boron neutron capture therapy
    Ogura, K
    Yamazaki, A
    Yanagie, H
    Eriguchi, M
    Lehmann, EH
    Küehne, G
    Bayon, G
    Maruyama, K
    Kobayashi, H
    [J]. RADIATION MEASUREMENTS, 2001, 34 (1-6) : 555 - 558
  • [49] CONCEPTUAL DESIGN OF A MEDICAL REACTOR FOR NEUTRON-CAPTURE THERAPY
    NEUMAN, WA
    JONES, JL
    [J]. NUCLEAR TECHNOLOGY, 1990, 92 (01) : 77 - 92
  • [50] Optimization of the epithermal neutron beam for boron neutron capture therapy at the Brookhaven Medical Research Reactor
    Hu, JP
    Rorer, DC
    Reciniello, RN
    Holden, NE
    [J]. REACTOR DOSIMETRY IN THE 21ST CENTURY, 2003, : 315 - 322