PREDICTION OF RESPONSE TO METHOTREXATE IN PATIENTS WITH RHEUMATOID ARTHRITIS: A MACHINE LEARNING APPROACH USING CLINICAL TRIAL DATA

被引:0
|
作者
Duong, S. [1 ]
Crowson, C. S. [1 ]
Athreya, A. [2 ]
Atkinson, E. [1 ]
Davis, J. M., III [3 ]
Warrington, K. J. [1 ]
Matteson, E.
Weinshilboum, R. [2 ]
Wang, L. [2 ]
Myasoedova, E. [3 ]
机构
[1] Mayo Clin, Quantitat Hlth Sci, Rochester, MN USA
[2] Mayo Clin, Mol Pharmacol & Expt Therapeut, Rochester, MN USA
[3] Mayo Clin, Internal Med, Rheumatol, Rochester, MN USA
关键词
D O I
10.1136/annrheumdis-2022-eular.891
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
POS0514
引用
收藏
页码:513 / 514
页数:2
相关论文
共 50 条
  • [1] Clinical predictors of response to methotrexate in patients with rheumatoid arthritis: a machine learning approach using clinical trial data
    Duong, Stephanie Q.
    Crowson, Cynthia S.
    Athreya, Arjun
    Atkinson, Elizabeth J.
    Davis, John M.
    Warrington, Kenneth J.
    Matteson, Eric L.
    Weinshilboum, Richard
    Wang, Liewei
    Myasoedova, Elena
    ARTHRITIS RESEARCH & THERAPY, 2022, 24 (01)
  • [2] Clinical predictors of response to methotrexate in patients with rheumatoid arthritis: a machine learning approach using clinical trial data
    Stephanie Q. Duong
    Cynthia S. Crowson
    Arjun Athreya
    Elizabeth J. Atkinson
    John M. Davis
    Kenneth J. Warrington
    Eric L. Matteson
    Richard Weinshilboum
    Liewei Wang
    Elena Myasoedova
    Arthritis Research & Therapy, 24
  • [3] Identification of a Rule to Predict Response to Sarilumab in Patients with Rheumatoid Arthritis Using Machine Learning and Clinical Trial Data
    Rehberg, Markus
    Giegerich, Clemens
    Praestgaard, Amy
    van Hoogstraten, Hubert
    Iglesias-Rodriguez, Melitza
    Curtis, Jeffrey R.
    Gottenberg, Jacques-Eric
    Schwarting, Andreas
    Castaneda, Santos
    Roth, Andrea Rubbert
    Choy, Ernest
    ARTHRITIS & RHEUMATOLOGY, 2020, 72
  • [4] Identification of a Rule to Predict Response to Sarilumab in Patients with Rheumatoid Arthritis Using Machine Learning and Clinical Trial Data
    Rehberg, Markus
    Giegerich, Clemens
    Praestgaard, Amy
    van Hoogstraten, Hubert
    Iglesias-Rodriguez, Melitza
    Curtis, Jeffrey R.
    Gottenberg, Jacques-Eric
    Schwarting, Andreas
    Castaneda, Santos
    Rubbert-Roth, Andrea
    Choy, Ernest H. S.
    RHEUMATOLOGY AND THERAPY, 2021, 8 (04) : 1661 - 1675
  • [5] Identification of a Rule to Predict Response to Sarilumab in Patients with Rheumatoid Arthritis Using Machine Learning and Clinical Trial Data
    Markus Rehberg
    Clemens Giegerich
    Amy Praestgaard
    Hubert van Hoogstraten
    Melitza Iglesias-Rodriguez
    Jeffrey R. Curtis
    Jacques-Eric Gottenberg
    Andreas Schwarting
    Santos Castañeda
    Andrea Rubbert-Roth
    Ernest H. S. Choy
    Rheumatology and Therapy, 2021, 8 : 1661 - 1675
  • [6] Individualized Prediction of Response to Methotrexate Treatment in Patients with Rheumatoid Arthritis: A Pharmacogenomics-driven Machine Learning Approach
    Myasoedova, Elena
    Athreya, Arjun
    Crowson, Cynthia
    Weinshilboum, Richard
    Wang, Liewei
    Matteson, Eric
    ARTHRITIS & RHEUMATOLOGY, 2020, 72
  • [7] PHARMACOGENOMICS-DRIVEN INDIVIDUALIZED PREDICTION OF TREATMENT RESPONSE TO METHOTREXATE IN PATIENTS WITH RHEUMATOID ARTHRITIS: A MACHINE LEARNING APPROACH
    Myasoedova, E.
    Athreya, A.
    Crowson, C. S.
    Weinshilboum, R.
    Wang, L.
    Matteson, E.
    ANNALS OF THE RHEUMATIC DISEASES, 2020, 79 : 594 - 594
  • [8] Machine learning using genetic and clinical data identifies a signature that robustly predicts methotrexate response in rheumatoid arthritis
    Lim, Lee Jin
    Lim, Ashley J. W.
    Ooi, Brandon N. S.
    Tan, Justina Wei Lynn
    Koh, Ee Tzun
    Group, Ttsh Rheumatoid Arthritis Study
    Chong, Samuel S.
    Khor, Chiea Chuen
    Tucker-Kellogg, Lisa
    Lee, Caroline G.
    Leong, Khai Pang
    RHEUMATOLOGY, 2022, 61 (10) : 4175 - 4186
  • [9] Toward Individualized Prediction of Response to Methotrexate in Early Rheumatoid Arthritis: A Pharmacogenomics-Driven Machine Learning Approach
    Myasoedova, Elena
    Athreya, Arjun P.
    Crowson, Cynthia S.
    Davis, John M.
    Warrington, Kenneth J.
    Walchak, Robert C.
    Carlson, Erin
    Kalari, Krishna R.
    Bongartz, Tim
    Tak, Paul P.
    van Vollenhoven, Ronald F.
    Padyukov, Leonid
    Emery, Paul
    Morgan, Ann
    Wang, Liewei
    Weinshilboum, Richard M.
    Matteson, Eric L.
    ARTHRITIS CARE & RESEARCH, 2022, 74 (06) : 879 - 888
  • [10] PREDICTION OF RESPONSE OF METHOTREXATE IN PATIENTS WITH RHEUMATOID ARTHRITIS USING SERUM LIPIDOMICS
    Maciejewski, Mateusz
    Sands, Caroline
    Nair, Nisha
    Ling, Stephanie
    Verstappen, Suzanne
    Hyrich, Kimme
    Rams, Matura
    Barton, Anne
    Ziemek, Daniel
    Lewis, Matthew
    Plant, Darren
    RHEUMATOLOGY, 2020, 59