Characterization of a pectic polysaccharide from the fruit of Ziziphus jujuba

被引:43
|
作者
Zhao, Zhihui
Dai, Hui
Wu, Xiangmei
Chang, Haitao
Gao, Xiaoming
Liu, Mengjun
Tu, Pengfei [1 ]
机构
[1] Univ Agr, Res Ctr Chinese Jujube, Baoding 071001, hebei, Peoples R China
[2] Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, Modern Res Ctr Tradit Chinese Med, Beijing 100083, Peoples R China
[3] Peking Univ, Hlth Sci Ctr, Sch Basic Med Sci, Beijing 100083, Peoples R China
关键词
Ziziphus jujuba Mill cv. jinsixiaozao Hort; fruit; pectic polysaccharide; immunological activity;
D O I
10.1007/s10600-007-0141-y
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
A pectic polysaccharide was isolated from the fruits of Ziziphus jujuba Mill. cv. jinsixiaozao Hort. and its structure was characterized by acid hydrolysis, methylation, and NMR spectroscopies. The purified fraction Ju-B-7 had a molecular mass of over 2000 kDa. Chemical and spectroscopic analyses indicated that Ju-B-7 is composed mainly of alpha-1,4-linked D-galactopyranosyluronic acid and 1,2-linked L-rhamnose with a molar ratio of 8.1:1. It can significantly stimulate spleen cell proliferation in vitro (P < 0.01, 10 mu mg/mL).
引用
收藏
页码:374 / 376
页数:3
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