Structural properties and antibacterial potency of new supramolecular organotin(IV) dithiocarboxylates

A series of new organotin(IV) derivatives: Me3SnL (1), Bu3SnL (2), Ph3SnL (3), Me2SnCIL (4), Bu2SnClL (5). Ph2SnClL (6), Et2SnClL (7) and Et2SnL2 (8) where L = N-(2,3-dimethylphenyl)piperazine-1-carbodithioate have been synthesized and characterized by various analytical techniques. Among these techniques, H-1 and C-13 NMR were carried out to asses solution structures whereas the solid state structures were confirmed by FT-IR and X-ray single crystal analysis (3, 5 and 8). Crystal structure of complex (3) and (5) showed distorted trigonal bipyramidal geometry and square pyramidal geometry, respectively. The inclination of the structure 5 towards square-pyramidal may be due to the presence of the Sn-Cl center dot center dot center dot HN-piperazine hydrogen bonds between the adjacent molecules. A supramolecular structure is shown by compound (8), with central tin atom exists in a distorted octahedral geometry. The antibacterial results indicated the profound activity of the compounds against various strains of bacteria. In addition to this, the triorganotin(IV) derivatives were found more active than diorganotin(IV) compounds. (C) 2011 Elsevier Ltd. All rights reserved.