Phosphatidylserine promotes polar Cdc42 localization

被引:1
|
作者
Freisinger, Tina [1 ]
Wedlich-Soeldner, Roland [1 ]
机构
[1] Max Planck Inst Biochem, D-82152 Martinsried, Germany
关键词
YEAST PLASMA-MEMBRANE; PROTEIN LOCALIZATION; SURFACE-CHARGE;
D O I
10.1038/ncb2382
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The establishment and maintenance of cell polarity requires targeted recruitment of polarity regulators to the plasma membrane. Phosphatidylserine is now shown to have a key role in polarization of yeast cells and the localization of the central polarity regulator Cdc42.
引用
收藏
页码:1387 / 1388
页数:2
相关论文
共 50 条
  • [41] HCF-1 promotes cell cycle progression by regulating the expression of CDC42
    Xiang, Pan
    Li, Fei
    Ma, Zhihua
    Yue, Jiping
    Lu, Cailing
    You, Yuangang
    Hou, Lin
    Yin, Bin
    Qiang, Boqin
    Shu, Pengcheng
    Peng, Xiaozhong
    [J]. CELL DEATH & DISEASE, 2020, 11 (10)
  • [42] HCF-1 promotes cell cycle progression by regulating the expression of CDC42
    Pan Xiang
    Fei Li
    Zhihua Ma
    Jiping Yue
    Cailing Lu
    Yuangang You
    Lin Hou
    Bin Yin
    Boqin Qiang
    Pengcheng Shu
    Xiaozhong Peng
    [J]. Cell Death & Disease, 11
  • [43] Activation of Rho GTPase Cdc42 promotes adhesion and invasion in colorectal cancer cells
    Gao, Lei
    Bai, Lan
    Nan, Qing-zhen
    [J]. MEDICAL SCIENCE MONITOR BASIC RESEARCH, 2013, 19 : 201 - 207
  • [44] Bacterial infection promotes tumorigenesis of colorectal cancer via regulating CDC42 acetylation
    Wang, Dan-Ni
    Ni, Jin-Jing
    Li, Jian-Hui
    Gao, Ya-Qi
    Ni, Fang-Jing
    Zhang, Zhen-Zhen
    Fang, Jing-Yuan
    Lu, Jie
    Yao, Yu-Feng
    [J]. PLOS PATHOGENS, 2023, 19 (02)
  • [45] Porphyromonas gingivalis lipopolysaccharide activates platelet Cdc42 and promotes platelet spreading and thrombosis
    Senini, Vincent
    Amara, Umme
    Paul, Manoj
    Kim, Hugh
    [J]. JOURNAL OF PERIODONTOLOGY, 2019, 90 (11) : 1336 - 1345
  • [46] Cdc42 activity and cortactin co-localization with perinuclear actin during ischemia
    Hallett, MA
    Atkinson, SJ
    [J]. MOLECULAR BIOLOGY OF THE CELL, 2001, 12 : 298A - 298A
  • [47] Cdc42 activation state affects its localization and protein levels in fission yeast
    Estravis, Miguel
    Rincon, Sergio Antonio
    Portales, Elvira
    Perez, Pilar
    Santos, Beatriz
    [J]. MICROBIOLOGY-SGM, 2017, 163 (08): : 1156 - 1166
  • [48] Full activation of WASP, not N-WASP, by Cdc42 and PIP2 requires Cdc42 prenylation
    Dey, Souvik
    Zhou, Huan-Xiang
    [J]. BIOPHYSICAL JOURNAL, 2023, 122 (03) : 62A - 62A
  • [49] Spatial analysis of Cdc42 activity reveals a role for plasma membrane-associated Cdc42 in centrosome regulation
    Herrington, Kari A.
    Trinh, Andrew L.
    Dang, Carolyn
    O'Shaughnessy, Ellen
    Hahn, Klaus M.
    Gratton, Enrico
    Digman, Michelle A.
    Sutterlin, Christine
    [J]. MOLECULAR BIOLOGY OF THE CELL, 2017, 28 (15) : 2135 - 2145
  • [50] Cdc42 activation couples spindle positioning to first polar body formation in oocyte maturation
    Ma, CQ
    Benink, HA
    Cheng, DY
    Montplaisir, W
    Wang, L
    Xi, YW
    Zheng, PP
    Bement, WM
    Liu, XJ
    [J]. CURRENT BIOLOGY, 2006, 16 (02) : 214 - 220