Impedimetric Aptamer-Based Biosensors: Applications

被引:13
|
作者
Preuss, John-Alexander [1 ]
Reich, Peggy [1 ]
Bahner, Nicole [2 ]
Bahnemann, Janina [1 ]
机构
[1] Leibniz Univ Hannover, Inst Tech Chem, Hannover, Germany
[2] Hsch Mannheim, Inst Biol Verfahrenstech, Mannheim, Germany
来源
APTAMERS IN BIOTECHNOLOGY | 2020年 / 174卷
关键词
Aptamer; Aptasensor; Bacteria; Biomarker; Biosensor; Cancer; Contaminants; Diagnostics; Disease; Drug; Environmental; Food industry; Health care; Impedance; Infection; Monitoring; Pathogen; Point-of-care; Serum; Therapy; Toxins; Tumor marker; Virus; LABEL-FREE DETECTION; C-REACTIVE PROTEIN; CARDIAC TROPONIN-I; REDUCED GRAPHENE OXIDE; SENSITIVE ELECTROCHEMICAL APTASENSOR; ULTRASENSITIVE DETECTION; SELECTIVE DETECTION; IMPEDANCE APTASENSOR; SALMONELLA-TYPHIMURIUM; STAPHYLOCOCCUS-AUREUS;
D O I
10.1007/10_2020_125
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Impedimetric aptamer-based biosensors show high potential for handheld devices and point-of-care tests. In this review, we report on recent advances in aptamer-based impedimetric biosensors for applications in biotechnology. We detail on analytes relevant in medical and environmental biotechnology as well as food control, for which aptamer-based impedimetric biosensors were developed. The reviewed biosensors are examined for their performance, including sensitivity, selectivity, response time, and real sample validation. Additionally, the benefits and challenges of impedimetric aptasensors are summarized.
引用
收藏
页码:43 / 91
页数:49
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