One-step homozygosity in precise gene editing by an improved CRISPR/Cas9 system

被引：13

作者：

Zhao, Pei ^{[1
,2
,3
]}

Zhang, Zhe ^{[1
,2
]}

Lv, Xiaoying ^{[4
]}

Zhao, Xiang ^{[1
,2
]}

Suehiro, Yuji ^{[5
,6
]}

Jiang, Yinan ^{[4
]}

Wang, Xinquan ^{[4
]}

Mitani, Shohei ^{[5
,6
]}

Gong, Haipeng ^{[4
]}

Xue, Ding ^{[1
,2
,7
]}

机构：

[1] Tsinghua Univ, Sch Life Sci, Beijing 100084, Peoples R China

[2] Tsinghua Univ, Collaborat Innovat Ctr Diag & Treatment Infect Di, Beijing 100084, Peoples R China

[3] Tsinghua Univ, Peking Univ, Joint Ctr Life Sci, Beijing 100084, Peoples R China

[4] Tsinghua Univ, Sch Life Sci, Beijing 100084, Peoples R China

[5] Tokyo Womens Med Univ, Sch Med, Dept Physiol, Tokyo 1628666, Japan

[6] Japan Sci & Technol Agcy, CREST, Tokyo 1628666, Japan

[7] Univ Colorado, Dept Mol Cellular & Dev Biol, Boulder, CO 80309 USA

来源：

CELL RESEARCH | 2016年 / 26卷 / 05期

关键词：

CAENORHABDITIS-ELEGANS GENOME; C; ELEGANS; TARGET DNA; GUIDE RNA; CAS9;

D O I：

10.1038/cr.2016.46

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

引用

页码：633 / 636

页数：4

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