The cAMP effector EPAC activates the transcription factor Elk1 in prostate smooth muscle and is a minor regulator of α1-adrenergic prostate contraction

被引：0
|
作者：
Hennenberg, M. [1 ]
Strittmatter, F. [1 ]
Schmetkamp, H. [1 ]
Rutz, B. [1 ]
Walther, S. [1 ]
Roosen, A. [1 ]
Stief, C. G. [1 ]
Gratzke, C. [1 ]
机构：
[1] Univ Munich, Dept Urol, Munich, Germany
来源：
EUROPEAN UROLOGY SUPPLEMENTS | 2012年 / 11卷 / 01期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：E1 / U293
页数：2
相关论文
共 50 条
  • [21] Vascular injury activates the ELK1/SND1/SRF pathway to promote vascular smooth muscle cell proliferative phenotype and neointimal hyperplasia
    Su, Chao
    Liu, Mingxia
    Yao, Xuyang
    Hao, Wei
    Ma, Jinzheng
    Ren, Yuanyuan
    Gao, Xingjie
    Xin, Lingbiao
    Ge, Lin
    Yu, Ying
    Wei, Minxin
    Yang, Jie
    CELLULAR AND MOLECULAR LIFE SCIENCES, 2024, 81 (01)
  • [22] Expression and alpha1-adrenergic regulation of caldesmon in human prostate smooth muscle
    Walther, S.
    Strittmatter, F.
    Rutz, B.
    Roosen, A.
    Heinzer, F.
    Stief, C. G.
    Gratzke, C.
    Hennenberg, M.
    EUROPEAN UROLOGY SUPPLEMENTS, 2012, 11 (01) : E110 - E110
  • [23] Comparative regulation of α1-adrenergic receptor mediated contraction in urogenitally derived smooth muscleEffect of epidermal growth factor
    F. J. Pereira
    P. Drescher
    D. Rauch
    P. O. Madsen
    J. A. Will
    Urological Research, 1997, 25 : S13 - S19
  • [24] Antagonism of?1-adrenoceptors by?3-adrenergic agonists: Structure-function relations of different agonists in prostate smooth muscle contraction
    Huang, Ru
    Tamalunas, Alexander
    Waidelich, Raphaela
    Strittmatter, Frank
    Stief, Christan G.
    Hennenberg, Martin
    BIOCHEMICAL PHARMACOLOGY, 2022, 202
  • [25] INHIBITION OF PROSTATE SMOOTH MUSCLE CONTRACTION BY INHIBITORS OF POLO-LIKE KINASES (PLK): AN ALPHA1-ADRENOCEPTOR-SPECIFIC ROLE FOR PLK1 IN SMOOTH MUSCLE CONTRACTION?
    Hennenberg, Martin
    Kuppermann, Paul
    Yu, Qingfeng
    Rutz, Beata
    Wang, Yiming
    Herlemann, Annika
    Waidelich, Raphaela
    Strittmatter, Frank
    Stief, Christian
    Gratzke, Christian
    JOURNAL OF UROLOGY, 2018, 199 (04): : E602 - E602
  • [26] THE ALPHA(1)-ADRENERGIC RECEPTOR THAT MEDIATES SMOOTH-MUSCLE CONTRACTION IN HUMAN PROSTATE HAS THE PHARMACOLOGICAL PROPERTIES OF THE CLONED HUMAN ALPHA(1C) SUBTYPE
    FORRAY, C
    BARD, JA
    WETZEL, JM
    CHIU, G
    SHAPIRO, E
    TANG, R
    LEPOR, H
    HARTIG, PR
    WEINSHANK, RL
    BRANCHEK, TA
    GLUCHOWSKI, C
    MOLECULAR PHARMACOLOGY, 1994, 45 (04) : 703 - 708
  • [27] inhibits neurogenic and a1-adrenergic human prostate smooth muscle contractions, with similar pharmacologic patterns as α1-blockers
    Huang, R.
    Liu, Y.
    Li, B.
    Wang, R.
    Tamalunas, A.
    Waidelich, R.
    Strittmatter, F.
    Stief, C. G.
    Hennenberg, M.
    EUROPEAN UROLOGY, 2021, 79 : S45 - S45
  • [28] Onvansertib, a polo-like kinase 1 inhibitor, inhibits prostate stromal cell growth and prostate smooth muscle contraction, which is additive to inhibition by α1-blockers
    Wang, Xiaolong
    Li, Bingsheng
    Ciotkowska, Anna
    Rutz, Beata
    Erlander, Mark G.
    Ridinger, Maya
    Wang, Ruixiao
    Tamalunas, Alexander
    Waidelich, Raphaela
    Stief, Christian G.
    Hennenberg, Martin
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2020, 873
  • [29] Androgen-regulated proliferation and gene transcription in a prostate smooth muscle cell line (PS-1)
    Gerdes, MJ
    Dang, TD
    Lu, B
    Larsen, M
    McBride, L
    Rowley, DR
    ENDOCRINOLOGY, 1996, 137 (03) : 864 - 872
  • [30] The cAMP responsive Rap1 guanine nucleotide exchange factor, Epac, induces smooth muscle relaxation by down regulation of RhoA activity
    Zieba, Bartosz Jakub
    Artamonov, Mykhaylo V.
    Jin, Li
    Momotani, Ko
    Ho, Ruoya
    Franke, Aaron S.
    Neppl, Ronald L.
    Stevenson, Andra S.
    Khromov, Alexander S.
    Chrzanowska-Wodnicka, Magdalena
    Somlyo, Avril V.
    FASEB JOURNAL, 2011, 25
12345