Tailor-made peptide sensor for detection of matrix metalloproteinase 2 in blood serum

被引:12
|
作者
Xu, Huifeng [1 ,2 ]
Ye, Hongzhi [2 ]
Yu, Lishuang [2 ]
Chi, Yuwu [1 ]
Liu, Xianxiang [2 ]
Chen, Guonan [1 ]
机构
[1] Fuzhou Univ, Dept Chem, Fujian Prov Key Lab Anal & Detect Food Safety, Minist Educ,Key Lab Anal & Detect Food Safety, Fuzhou 350002, Fujian, Peoples R China
[2] Fujian Univ Tradit Chinese Med, Acad Integrat Med, Fuzhou, Fujian, Peoples R China
关键词
FRET SENSOR; INHIBITORS; BIOSENSOR; AND-9; MMP-2;
D O I
10.1039/c5ay00666j
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Wedesigned a simple and sensitive peptide electrochemical sensor for detection of MMP-2, with a detection limit of 0.3 ng mL(-1). The sensor detected MMP-2 in a serum sample with satisfactory results. It was also used to assay an inhibitor of MMP-2.
引用
收藏
页码:5371 / 5374
页数:4
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