Thrombophilia and fetal germinal matrix-intraventricular hemorrhage: does it matter?

被引：12
|
作者：
Ramenghi, LA
Fumagalli, M
Righini, A
Triulzi, F
Kustermann, A
Mosca, F
机构：
[1] Univ Milan, IRCCS, L Mangiagalli Hosp, Neonatal Intens Care Unit, Milan, Italy
[2] Univ Milan, IRCCS, L Mangiagalli Hosp, Dept Obstet & Gynaecol, Milan, Italy
来源：
ULTRASOUND IN OBSTETRICS & GYNECOLOGY | 2005年 / 26卷 / 05期
关键词：
factor V Leiden; fetal hemorrhage; GMH-IVH; thrombophilia;
D O I：
10.1002/uog.2586
中图分类号：
O42 [声学];
学科分类号：
070206 ; 082403 ;
摘要：
Germinal matrix-intraventricular hemorrhage (GMH-IVH) in the fetus is very rare and the role of thrombophilia in its pathogenesis is unclear. We report on the prenatal diagnosis by magnetic resonance imaging of GMH-IVH in a 24-week fetus. The newborn presented posthemorrhagic ventriculomegaly and was found to be heterozygous for two thrombophilic patterns, factor V Leiden and methylenetetrahydrofolate reductase mutation. The combination of this hypercoagulable state and prenatal GMH-IVH is discussed together with the opportunity of testing these infants for thrombophilia. Copyright (c) 2005 ISUOG. Published by John Wiley & Sons, Ltd.
引用
收藏
页码：574 / 576
页数：3
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