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Thrombophilia and fetal germinal matrix-intraventricular hemorrhage: does it matter?
被引:12
|作者:
Ramenghi, LA
Fumagalli, M
Righini, A
Triulzi, F
Kustermann, A
Mosca, F
机构:
[1] Univ Milan, IRCCS, L Mangiagalli Hosp, Neonatal Intens Care Unit, Milan, Italy
[2] Univ Milan, IRCCS, L Mangiagalli Hosp, Dept Obstet & Gynaecol, Milan, Italy
关键词:
factor V Leiden;
fetal hemorrhage;
GMH-IVH;
thrombophilia;
D O I:
10.1002/uog.2586
中图分类号:
O42 [声学];
学科分类号:
070206 ;
082403 ;
摘要:
Germinal matrix-intraventricular hemorrhage (GMH-IVH) in the fetus is very rare and the role of thrombophilia in its pathogenesis is unclear. We report on the prenatal diagnosis by magnetic resonance imaging of GMH-IVH in a 24-week fetus. The newborn presented posthemorrhagic ventriculomegaly and was found to be heterozygous for two thrombophilic patterns, factor V Leiden and methylenetetrahydrofolate reductase mutation. The combination of this hypercoagulable state and prenatal GMH-IVH is discussed together with the opportunity of testing these infants for thrombophilia. Copyright (c) 2005 ISUOG. Published by John Wiley & Sons, Ltd.
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页码:574 / 576
页数:3
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