Exendin(9-39)amide suppresses GLP-1 insulinotropic action in rats infused with dimethyl ester of succinic acid.

被引:0
|
作者
Cancelas, J
Villanueva-Peñacarrillo, ML
Valverde, I
Malaisse, WJ
机构
[1] Fdn Jimenez Diaz, E-28040 Madrid, Spain
[2] Free Univ Brussels, Expt Med Lab, Brussels, Belgium
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
500
引用
收藏
页码:A131 / A131
页数:1
相关论文
共 38 条
  • [21] Value of the radiolabelled GLP-1 receptor antagonist exendin(9-39) for targeting of GLP-1 receptor-expressing pancreatic tissues in mice and humans
    Waser, Beatrice
    Reubi, Jean Claude
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2011, 38 (06) : 1054 - 1058
  • [22] Glucagon-Like Peptide (GLP)-1(9-36)Amide-Mediated Cytoprotection Is Blocked by Exendin(9-39) Yet Does Not Require the Known GLP-1 Receptor
    Ban, Kiwon
    Kim, Kyoung-Han
    Cho, Chan-Kyung
    Sauve, Meghan
    Diamandis, Eleftherios P.
    Backx, Peter H.
    Drucker, Daniel J.
    Husain, Mansoor
    [J]. ENDOCRINOLOGY, 2010, 151 (04) : 1520 - 1531
  • [23] Quantification of the Contribution of GLP-1 to Mediating Insulinotropic Effects of DPP-4 Inhibition With Vildagliptin in Healthy Subjects and Patients With Type 2 Diabetes Using Exendin [9-39] as a GLP-1 Receptor Antagonist
    Nauck, Michael A.
    Kind, Joachim
    Kthe, Lars D.
    Holst, Jens J.
    Deacon, Carolyn F.
    Broschag, Matthias
    He, Yan Ling
    Kjems, Lise
    Foley, James
    [J]. DIABETES, 2016, 65 (08) : 2440 - 2447
  • [24] The differential antiemetic properties of GLP-1 receptor antagonist, exendin (9-39) in Suncus murinus (house musk shrew)
    Chan, Sze Wa
    Lu, Zengbing
    Lin, Ge
    Yew, David Tai Wai
    Yeung, Chi Kong
    Rudd, John A.
    [J]. NEUROPHARMACOLOGY, 2014, 83 : 71 - 78
  • [25] EXENDIN-4 IS A HIGH-POTENCY AGONIST AND TRUNCATED EXENDIN (9-39)AMIDE AN ANTAGONIST AT THE GLP-1 (7-36)AMIDE RECEPTOR OF INSULIN-SECRETING BETA-CELLS
    GOKE, R
    FEHMANN, HC
    LINN, T
    SCHMIDT, H
    ENG, J
    GOKE, B
    [J]. DIGESTION, 1993, 54 (06) : 347 - 347
  • [26] Potentiation of glucagon-like peptide 1 insulinotropic action by succinic acid dimethyl ester
    LeclercqMeyer, V
    Malaisse, WJ
    [J]. LIFE SCIENCES, 1996, 58 (14) : 1195 - 1199
  • [27] CLONING AND FUNCTIONAL EXPRESSION OF THE HUMAN ISLET GLP-1 RECEPTOR - DEMONSTRATION THAT EXENDIN-4 IS AN AGONIST AND EXENDIN-(9-39) AN ANTAGONIST OF THE RECEPTOR
    THORENS, B
    PORRET, A
    BUHLER, L
    DENG, SP
    MOREL, P
    WIDMANN, C
    [J]. DIABETES, 1993, 42 (11) : 1678 - 1682
  • [28] Grape powder attenuates the negative effects of GLP-1 receptor antagonism by exendin-3 (9-39) in a normoglycemic mouse model
    Haufe, T. C.
    Gilley, A. D.
    Goodrich, K. M.
    Ryan, C. M.
    Smithson, A. T.
    Hulver, M. W.
    Liu, D.
    Neilson, A. P.
    [J]. FOOD & FUNCTION, 2016, 7 (06) : 2692 - 2705
  • [29] Chronic treatment of obese hyperglycaemic ob/ob mice with exendin(9-39)amide suggests a minor role for endogenous GLP-1 in metabolic abnormalities of obesity-diabetes
    Green, BD
    Irwin, N
    Gault, VA
    O'Harte, FPM
    Bailey, CJ
    Flatt, PR
    [J]. DIABETOLOGIA, 2004, 47 : A239 - A239
  • [30] Roles of endogenous GLP-1 in the glycaemic and energy expenditure responses to fat in type 2 diabetes studied using vildagliptin and exendin(9-39)
    Xie, C.
    Wang, X.
    Bound, M. J.
    Grivell, J.
    Jones, K. L.
    Horowitz, M.
    Little, T.
    Rayner, C. K.
    Wu, T.
    [J]. DIABETOLOGIA, 2019, 62 : S76 - S77