ULTRASOUND-ACCELERATED ONE-POT SYNTHESIS OF N-ACETYL-2-ARYL-1,2-DIHYDRO-4H-3,1-BENZOXAZIN-4-ONES

被引：9
|
作者：
Azarifar, D. [1 ]
Sheikh, D. [1 ]
机构：
[1] Univ Bu Ali Sina, Dept Chem, Hamadan 65178, Iran
来源：
CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2011年 / 47卷 / 09期
关键词：
acetic anhydride; N-acetyl-2-aryl-1,2-dihydro-4H-3,1-benzoxazin-4-one; anthranilic acid; heteroaromatic aldehyde; ultrasound; HUMAN-LEUKOCYTE ELASTASE; DICARBOXYLIC-ACIDS; CHYMOTRYPSIN; INHIBITION; 4H-3,1-BENZOXAZIN-4-ONES; BENZOXAZINONES; INACTIVATION; CHEMISTRY; PROTEASE; ALPHA;
D O I：
10.1007/s10593-011-0883-0
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The one-pot synthesis of N-acetyl-2-aryl-1,2-dihydro-4H-3,1-benzoxazin-4-one derivatives from the condensation reaction of anthranilic acids with heteroaromatic aldehydes in the presence of excess amount of acetic anhydride has been explored. The reactions proceed smoothly under ultrasound irradiation and without catalyst at 35-40 degrees C to afford the title products in high yields.
引用
收藏
页码：1128 / 1136
页数：9
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