Enhancing prime editing efficiency by modified pegRNA with RNA G-quadruplexes

被引:38
|
作者
Li, Xiangyang [1 ,2 ]
Wang, Xin [1 ,2 ]
Sun, Wenjun [1 ,2 ]
Huang, Shisheng [1 ,2 ]
Zhong, Mingtian [3 ]
Yao, Yuan [4 ]
Ji, Quanjiang [5 ]
Huang, Xingxu [1 ,6 ]
机构
[1] ShanghaiTech Univ, Gene Editing Ctr, Sch Life Sci & Technol, Shanghai 201210, Peoples R China
[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
[3] South China Normal Univ, Guangdong Key Lab Mental Hlth & Cognit Sci, Ctr Studies Psychol Applicat, Inst Brain Res & Rehabil, Guangzhou 510631, Peoples R China
[4] Zhejiang Univ, Hangzhou Global Sci & Technol Innovat Ctr, Hangzhou 311215, Peoples R China
[5] ShanghaiTech Univ, Sch Phys Sci & Technol, Shanghai 201210, Peoples R China
[6] Guangzhou Int Bio Isl, Guangzhou Lab, Guangzhou 510005, Peoples R China
关键词
STABILITY;
D O I
10.1093/jmcb/mjac022
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页数:4
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