Lipase-catalyzed resolution of 2-azabicyclo[2.2.1]hept-5-en-3-ones

被引：21
|
作者：
Nakano, H [1 ]
Iwasa, K [1 ]
Okuyama, Y [1 ]
Hongo, H [1 ]
机构：
[1] TOHOKU COLL PHARMACEUT SCI,AOBA KU,SENDAI,MIYAGI 981,JAPAN
来源：
TETRAHEDRON-ASYMMETRY | 1996年 / 7卷 / 08期
关键词：
D O I：
10.1016/0957-4166(96)00293-5
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The lipase-catalyzed asymmetric resolution of 2-azabicyclo[2.2.1] hept-5-en-3-ones is reported; non-racemic chiral 2-azabicyclo[2.2.1]hept-5-en-3-ones were obtained conveniently by lipase-catalyzed enantioselective transesterification or hydrolysis of N-hydroxymethyl-2-azabicyclo[2.2.1]hept-5-en-3-one or N-acyloxymethyl-2-azabicyclo[2.2.1]hept-5-en-3-one.
引用
收藏
页码：2381 / 2386
页数：6
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