Snapshots through an enzyme mechanism: Thymidylate synthase.

被引:0
|
作者
Stroud, RM [1 ]
FinerMoore, JS [1 ]
Stout, TJ [1 ]
Rutenber, EE [1 ]
机构
[1] UNIV CALIF SAN FRANCISCO, DEPT BIOCHEM & BIOPHYS, SAN FRANCISCO, CA 94143 USA
关键词
D O I
暂无
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
引用
收藏
页码:SUAM3 / SUAM3
页数:1
相关论文
共 50 条
  • [21] Mechanism of Naphthoquinone Selectivity of Thymidylate Synthase ThyX
    Myllykallio, Hannu
    Becker, Hubert F.
    Aleksandrov, Alexey
    BIOPHYSICAL JOURNAL, 2020, 119 (12) : 2508 - 2516
  • [22] Understanding the functions and specificities of maize branching enzyme and starch synthase.
    Guan, HP
    ImparlRadosevich, J
    Li, P
    Zhang, L
    Gao, Z
    Sun, JT
    Keeling, P
    PLANT PHYSIOLOGY, 1997, 114 (03) : 154 - 154
  • [23] Concerted versus Stepwise Mechanism in Thymidylate Synthase
    Islam, Zahidul
    Strutzenberg, Timothy S.
    Gurevic, Ilya
    Kohen, Amnon
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2014, 136 (28) : 9850 - 9853
  • [24] Structure-based discovery and in-parallel optimization of novel competitive inhibitors of thymidylate synthase.
    Sholchet, BK
    Tondi, D
    Slomczynska, U
    Ghelli, S
    Watterson, DM
    Costi, MP
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1999, 217 : U704 - U704
  • [25] Model chemical studies of thymidylate synthase. Nucleophilic addition of hydroxylamine to uracil and 5-fluorouracil.
    Costi, MP
    Rastelli, G
    Rinaldi, M
    Cevolani, M
    Pecorari, P
    FARMACO, 1996, 51 (03): : 209 - 214
  • [26] Recombinant squalene synthase. A mechanism for the rearrangement of presqualene diphosphate to squalene
    Blagg, BSJ
    Jarstfer, MB
    Rogers, DH
    Poulter, CD
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (30) : 8846 - 8853
  • [27] Geranylgeranylglyceryl phosphate synthase.: Characterization of the recombinant enzyme from Methanobacterium thermoautotrophicum
    Soderberg, T
    Chen, AJ
    Poulter, CD
    BIOCHEMISTRY, 2001, 40 (49) : 14847 - 14854
  • [28] PAIRWISE SPECIFICITY AND SEQUENTIAL BINDING IN ENZYME CATALYSIS - THYMIDYLATE SYNTHASE
    FINERMOORE, JS
    MONTFORT, WR
    STROUD, RM
    BIOCHEMISTRY, 1990, 29 (30) : 6977 - 6986
  • [29] Autoinhibition of neuronal NO synthase.
    Kotsonis, P
    Frey, A
    Fröhlich, LG
    Hofmann, H
    Reif, A
    Wink, DA
    Feelisch, M
    Schmidt, HHHW
    FASEB JOURNAL, 1999, 13 (04): : A132 - A132
  • [30] STRUCTURAL INSIGHTS INTO THE MECHANISM OF THYMIDYLATE SYNTHASE COMPLEMENTING PROTEINS
    Mathews, I. I.
    Deacon, A. M.
    McMullan, D.
    Canaves, J. M.
    Kuhn, P.
    Lesley, S.
    ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2002, 58 : C106 - C106