The Engineering of Brown Fat

被引：18
|
作者：
Christian, Mark [1 ]
Parker, Malcolm G. [1 ]
机构：
[1] Univ London Imperial Coll Sci Technol & Med, Inst Reprod & Dev Biol, London W12 0NN, England
来源：
JOURNAL OF MOLECULAR CELL BIOLOGY | 2010年 / 2卷 / 01期
关键词：
TRANSCRIPTIONAL COMPLEX; WHITE ADIPOCYTES; ADIPOSE-TISSUE; EXPRESSION; SWITCH;
D O I：
10.1093/jmcb/mjp035
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The developmental origins of brown adipose tissue and white adipose tissue are distinct, with brown adipocytes being derived from muscle precursors. PR domain containing 16, together with C/EBP beta, forms a lineage-switching transcriptional complex which promotes brown fat differentiation and suppresses muscle cell differentiation.
引用
收藏
页码：23 / 25
页数：3
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