5-cinnamoyl- and 5-(ethoxycarbonyl)-6-styryl derivatives of 4-aryl-3,4-dihydropyrimidin-2(1H)-ones

被引：15

作者：

Kolosov, Maksim A.

Orlov, Valeriy D.

Vashchenko, Valeriy V.

Shishkina, Svetlana V.

Shishkinb, Oleg V.

机构：

[1] Kharkov Natl Univ, Dept Organ Chem, UA-61077 Kharkov, Ukraine

[2] Natl Acad Sci Ukraine, Kharkov Single Crystals Inst, State Sci Inst, Kharkov, Ukraine

来源：

COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS | 2007年 / 72卷 / 09期

关键词：

5-acetyl-4-aryl-3,4-dihydropyrimidin-2(1H)-ones; pyrimidines; benzaldehydes; chalcones; Claisen-Schmidt reactions; cinnamoyl derivatives;

D O I：

10.1135/cccc20071219

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Several 5-cinnamoyl- and 5-(ethoxycarbonyl)-6-styryl derivatives of 4-aryl-3,4-dihydropyrimidin-2(1H)-ones were obtained and their physicochemical properties were investigated. The introduction of alkyl substituent in position 1 of dihydropyrimidine ring was shown to promote the Claisen-Schmidt reaction on acetyl group only; without the alkyl both acetyl and 6-methyl groups participate in the reaction.

引用

页码：1219 / 1228

页数：10

共 50 条

[21] Characterization of 5-ethoxycarbonyl-4-substituted-6-methyl-3,4-dihydropyrimidin-2 (1H)-ones using EI-TOF mass spectrometry
Salehi, H
Li, QR
Yin, H
Guo, QX
Xue, S
CHINESE JOURNAL OF CHEMICAL PHYSICS, 2005, 18 (05) : 786 - 792
[22] Synthesis of new 4-aryl-3, 4-dihydropyrimidin-2(1H)-ones/ thiones/ imines and their antimicrobial evaluation
Sandhya Rani, N.
Subba Reddy, G.V.
Jaya Veera, K.N.
Journal of Chemical and Pharmaceutical Research, 2014, 6 (02) : 373 - 379
[23] 1-Methyl-2-oxopyrrolidinium perchlorate ionic liquid in synthesis of 5-ethoxycarbonyl-3,4-dihydropyrimidin-2(1H)-ones
Badalova, G. N.
Abbasov, V. M.
Valiyev, I. A.
Alieva, L. I.
Talybov, A. H.
RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2017, 87 (11) : 2739 - 2743
[24] 1-Methyl-2-oxopyrrolidinium perchlorate ionic liquid in synthesis of 5-ethoxycarbonyl-3,4-dihydropyrimidin-2(1H)-ones
G. N. Badalova
V. M. Abbasov
I. A. Valiyev
L. I. Alieva
A. H. Talybov
Russian Journal of General Chemistry, 2017, 87 : 2739 - 2743
[25] Photo-oxidation of 5-acetyl-3,4-dihydropyrimidin-2(1H)-ones
Memarian, Hamid Reza
Farhadi, Asadollah
Sabzyan, Hassan
Soleymani, Mousa
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2010, 209 (2-3) : 95 - 103
[26] Expedient synthesis of 5-unsubstituted 3,4-dihydropyrimidin-2(1H)-ones.
Steele, TG
Coburn, CA
Patane, MA
Bock, MG
TETRAHEDRON LETTERS, 1998, 39 (51) : 9315 - 9318
[27] Synthesis and reactions of Biginelli-compounds. Part 23: Chemoenzymatic syntheses of enantiomerically pure 4-aryl-3,4-dihydropyrimidin-2(1H)-ones
Schnell, Barbara
Krenn, Wolfram
Faber, Kurt
Kappe, C. Oliver
Journal of the Chemical Society, Perkin Transactions 1, 2000, (24): : 4382 - 4389
[28] Ultrasound-assisted dehydrogenation of 5-acetyl-3,4-dihydropyrimidin-2(1H)-ones
Memarian, Hamid Reza
Farhadi, Asadollah
Sabzyan, Hassan
ULTRASONICS SONOCHEMISTRY, 2010, 17 (03) : 579 - 586
[29] Oxidation of 3,4-dihydropyrimidin-2(1H)-ones with nitrosonium(NO~+)
Rui Rui Liang
ChineseChemicalLetters, 2009, 20 (10) : 1183 - 1186
[30] Synthesis and Acylation of 4-Chloroalkyl-3,4-dihydropyrimidin-2(1H)-ones
Kolosov, Maksim A.
Kulyk, Olesia G.
Al-Ogaili, Muataz
Orlov, Valeriy D.
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 2012, 67 (09): : 921 - 924

← 1 2 3 4 5 →