Nanofluidic biosensing for β-amyloid detection using surface enhanced Raman spectroscopy

被引：179
|
作者：
Chou, I-Hsien [1 ]
Benford, Melodie [1 ]
Beier, Hope T. [1 ]
Cote, Gerard L. [1 ]
Wang, Miao [2 ]
Jing, Nan [2 ]
Kameoka, Jun [2 ]
Good, Theresa A. [3 ]
机构：
[1] Texas A&M Univ, Dept Biomed Engn, College Stn, TX 77843 USA
[2] Texas A&M Univ, Dept Elect Engn, College Stn, TX 77843 USA
[3] Univ Maryland Baltimore Cty, Dept Chem & Biochem Engn, Baltimore, MD 21250 USA
来源：
NANO LETTERS | 2008年 / 8卷 / 06期
关键词：
D O I：
10.1021/nl0808132
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Trace detection of the conformational transition of beta-amyloid peptide (A beta) from a predominantly alpha-helical structure to beta-sheet could have a large impact in understanding and diagnosing Alzheimer's disease. We demonstrate how a novel nanofluidic biosensor using a controlled, reproducible surface enhanced Raman spectroscopy active site was developed to observe A beta in different conformational states during the A beta self-assembly process as well as to distinguish A beta from confounder proteins commonly found in cerebral spinal fluid.
引用
收藏
页码：1729 / 1735
页数：7
相关论文
共 50 条
  • [41] Inkjet-fabricated Surface Enhanced Raman Spectroscopy (SERS) Sensors on Paper for Biosensing
    Restaino, Stephen M.
    White, Ian M.
    Optics and Biophotonics in Low-Resource Settings, 2015, 9314
  • [42] Viral biosensing based on novel nanofabricated surface-enhanced Raman spectroscopy substrates
    Shanmukh, Saratchandra
    Chaney, Stephen B.
    Jones, Les
    Tripp, Ralph A.
    Zhao, Yiping
    Dluhy, Richard A.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 231
  • [43] Sustained and Cost Effective Silver Substrate for Surface Enhanced Raman Spectroscopy Based Biosensing
    Ju, Jian
    Liu, Wei
    Perlaki, Clint Michael
    Chen, Keren
    Feng, Chunhua
    Liu, Quan
    SCIENTIFIC REPORTS, 2017, 7
  • [44] Sustained and Cost Effective Silver Substrate for Surface Enhanced Raman Spectroscopy Based Biosensing
    Jian Ju
    Wei Liu
    Clint Michael Perlaki
    Keren Chen
    Chunhua Feng
    Quan Liu
    Scientific Reports, 7
  • [45] Surface-Enhanced Raman Spectroscopy on Engineered Plasmonic Metamaterials for "label free" Biosensing
    Rippa, Massimo
    Capasso, Rossella
    Pannico, Marianna
    La Manna, Pietro
    Musto, Pellegrino
    Bobeico, Eugenia
    Zhou, Jun
    Petti, Lucia
    PLASMONICS: METALLIC NANOSTRUCTURES AND THEIR OPTICAL PROPERTIES XIII, 2015, 9547
  • [46] Sensitive and selective chem/biosensing based on surface-enhanced Raman spectroscopy (SERS)
    Zhang, Xiaoyu
    Shah, Nilam C.
    Van Duyne, Richard P.
    VIBRATIONAL SPECTROSCOPY, 2006, 42 (01) : 2 - 8
  • [47] Raman and surface-enhanced Raman scattering (SERS) biosensing
    Prochazka, M.
    OPTICAL SENSORS 2013, 2013, 8774
  • [48] Designing dendronic-Raman markers for sensitive detection using surface-enhanced Raman spectroscopy
    Jain, Priyanka
    Patra, Robi Sankar
    Rajaram, Sridhar
    Narayana, Chandrabhas
    RSC ADVANCES, 2019, 9 (48) : 28222 - 28227
  • [49] Surface-enhanced Raman spectroscopy for detection of toxic amyloid β oligomers adsorbed on self-assembled monolayers
    Voiciuk, Vladislava
    Valincius, Gintaras
    Budvytyte, Rima
    Matijoska, Algirdas
    Matulaitiene, Ieva
    Niaura, Gediminas
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2012, 95 : 526 - 532
  • [50] Quinoline yellow acts as a novel amyloid fibrillation probe by using surface-enhanced Raman spectroscopy
    Zhang, Lixia
    Zhao, Junqi
    Jiang, Guangyu
    Chen, Zhijun
    TALANTA, 2024, 280
12345