Digital clubbing: forms, associations and pathophysiology

被引:8
|
作者
Dubrey, Simon [1 ]
Pal, Shrestha [2 ]
Singh, Sarneet [3 ]
Karagiannis, Georgios [1 ]
机构
[1] Hillingdon & Mt Vernon Hosp NHS Fdn Trust, Dept Cardiol, Uxbridge UB8 3NN, Middx, England
[2] Hillingdon & Mt Vernon Hosp NHS Fdn Trust, Dept Cardiol, Gen Internal Med FY1, Uxbridge UB8 3NN, Middx, England
[3] Hillingdon & Mt Vernon Hosp NHS Fdn Trust, Dept Cardiol, Cardiol CT2, Uxbridge UB8 3NN, Middx, England
关键词
ENDOTHELIAL GROWTH-FACTOR; PRIMARY HYPERTROPHIC OSTEOARTHROPATHY; LUNG-CANCER PATIENTS; MUTATIONS; PATHOGENESIS; EXPRESSION; DIAGNOSIS; SLCO2A1;
D O I
10.12968/hmed.2016.77.7.403
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Among proposed mechanisms to explain digital clubbing, the release of cytokines, specifically vascular endothelial growth factor and platelet-derived growth factor, from aggregated platelets and megakaryocytes has emerged as the most likely explanation. This review describes these and other contributory processes.
引用
收藏
页码:403 / 408
页数:6
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