EXPOSURE RESPONSE ANALYSIS (PKPD) PREDICTS OPTIMAL EXPOSURE OF PRIDOPIDINE FOR CLINICAL EFFICACY OF FUNCTIONAL CAPACITY

被引:0
|
作者
Geva, Michal [1 ]
McGarry, Andrew [2 ]
Emek, Noga Gershoni [1 ]
Mehra, Munish [3 ]
Olanow, C. Warren [2 ]
Kieburtz, Karl [2 ]
Hayden, Michael R. [4 ,5 ]
机构
[1] Prilenia Neurotherapeut, Herzliyya, Israel
[2] Clintrex LLC, Sarasota, FL USA
[3] Tigermed, Gaithersburg, MD USA
[4] Prilenia Neurotherapeut, Naarden, Netherlands
[5] Univ British Columbia, Ctr Mol Med & Therapeut, Vancouver, BC, Canada
关键词
D O I
10.1136/jnnp-2021-EHDN.85
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
F42
引用
收藏
页码:A36 / A36
页数:1
相关论文
共 50 条
  • [21] Exposure-Response Analysis For Determination Of Benralizumab Optimal Dosing Regimen In Adults With Asthma
    Wang, B.
    Yan, L.
    Hutmacher, M.
    White, W. I.
    Ward, C. K.
    Nielsen, J.
    Wu, Y.
    Goldman, M.
    Raible, D. G.
    Roskos, L.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2014, 189
  • [22] Relationships between sorafenib exposure and clinical safety and efficacy
    Fukudo, Masahide
    ANNALS OF ONCOLOGY, 2015, 26 : 38 - 38
  • [23] The Clinical Efficacy of the Exposure Index Value in Computed Radiography
    Butler, M.
    Lewis, M.
    Rainford, L.
    MEDICAL PHYSICS, 2011, 38 (06)
  • [24] Voriconazole pharmacokinetics and exposure-response relationships: Assessing the links between exposure, efficacy and toxicity
    Dolton, Michael J.
    McLachlan, Andrew J.
    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2014, 44 (03) : 183 - 193
  • [25] Evaluating cardiac risk: exposure response analysis in early clinical drug development
    Grenier, Julie
    Paglialunga, Sabina
    Morimoto, Bruce H.
    Lester, Robert M.
    DRUG HEALTHCARE AND PATIENT SAFETY, 2018, 10 : 27 - 36
  • [26] Exposure and Response Prevention Process Predicts Treatment Outcome in Youth with OCD
    Kircanski, Katharina
    Peris, Tara S.
    JOURNAL OF ABNORMAL CHILD PSYCHOLOGY, 2015, 43 (03) : 543 - 552
  • [27] Prenatal cortisol exposure predicts infant cortisol response to acute stress
    O'Connor, Thomas G.
    Bergman, Kristin
    Sarkar, Pampa
    Glover, Vivette
    DEVELOPMENTAL PSYCHOBIOLOGY, 2013, 55 (02) : 145 - 155
  • [28] Exposure and Response Prevention Process Predicts Treatment Outcome in Youth with OCD
    Katharina Kircanski
    Tara S. Peris
    Journal of Abnormal Child Psychology, 2015, 43 : 543 - 552
  • [29] CLINICAL AND FUNCTIONAL EFFECTS OF ACCIDENTAL EXPOSURE TO IRRITANT GASES
    HUDSON, B
    FIELD, GB
    AUSTRALASIAN ANNALS OF MEDICINE, 1966, 15 (01): : 98 - &
  • [30] OPTIMAL DOSE OF TOCILIZUMAB FOR THE TREATMENT OF GIANT CELL ARTERITIS: EFFICACY, SAFETY, AND EXPOSURE-EFFICACY ANALYSIS FROM GIACTA
    Stone, J. H.
    Tuckwell, K.
    Dimonaco, S.
    Klearman, M.
    Mallalieu, N. L.
    Aringer, M.
    Blockmans, D.
    Brouwer, E.
    Cid, M. C.
    Dasgupta, B.
    Rech, J.
    Salvarani, C.
    Schett, G.
    Schulze-Koops, H.
    Spiera, R.
    Unizony, S. H.
    Collinson, N.
    ANNALS OF THE RHEUMATIC DISEASES, 2017, 76 : 107 - 108