Treatment of pouchitis, Crohn's disease, cuffitis, and other inflammatory disorders of the pouch: consensus guidelines from the International Ileal Pouch Consortium

被引：63

作者：

Shen, Bo ^{[1
]}

Kochhar, Gursimran S. ^{[5
]}

Rubin, David T. ^{[6
]}

Kane, Sunanda, V ^{[7
]}

Navaneethan, Udayakumar ^{[8
,9
]}

Bernstein, Charles N. ^{[10
]}

Cross, Raymond K. ^{[11
]}

Sugita, Akira ^{[12
,13
]}

Schairer, Jason ^{[14
]}

Kiran, Ravi P. ^{[2
]}

Fleshner, Philip ^{[15
]}

McCormick, James ^{[16
]}

D'Hoore, Andre ^{[17
]}

Shah, Samir A. ^{[18
,19
]}

Farraye, Francis A. ^{[20
]}

Kariv, Revital ^{[21
,22
]}

Liu, Xiuli ^{[23
]}

Rosh, Joel ^{[24
]}

Chang, Shannon ^{[25
]}

Scherl, Ellen ^{[26
]}

Schwartz, David A. ^{[27
]}

Kotze, Paulo Gustavo ^{[28
]}

Bruining, David H. ^{[7
]}

Philpott, Jessica ^{[29
]}

Abraham, Bincy ^{[30
,31
]}

Segal, Jonathan ^{[3
,32
]}

Sedano, Rocio ^{[33
]}

Kayal, Maia ^{[34
]}

Bentley-Hibbert, Stuart ^{[4
]}

Tarabar, Dino ^{[35
]}

El-Hachem, Sandra ^{[5
]}

Sehgal, Priya

Picoraro, Joseph A. ^{[36
]}

Vermeire, Severine ^{[37
]}

Sandborn, William J. ^{[38
]}

Silverberg, Mark S. ^{[39
]}

Pardi, Darrell S. ^{[7
]}

机构：

[1] Columbia Univ, Irving Med Ctr, New York Presbyterian Hosp, Ctr Intervent Inflammatory Bowel Dis, New York, NY 10032 USA

[2] Columbia Univ, Irving Med Ctr, New York Presbyterian Hosp, Div Colorectal Surg, New York, NY USA

[3] Columbia Univ, Irving Med Ctr, New York Presbyterian Hosp, Div Digest & Liver Dis, New York, NY USA

[4] Columbia Univ, Irving Med Ctr, New York Presbyterian Hosp, Dept Radiol, New York, NY USA

[5] Allegheny Hlth Network, Div Gastroenterol Hepatol & Nutr, Pittsburgh, PA USA

[6] Univ Chicago, Med Inflammatory Bowel Dis Ctr, Chicago, IL 60637 USA

[7] Mayo Clin, Div Gastroenterol & Hepatol, Rochester, MN USA

[8] Orlando Hlth, Ctr IBD, Digest Hlth Inst, Orlando, FL USA

[9] Orlando Hlth, Intervent IBD Unit, Digest Hlth Inst, Orlando, FL USA

[10] Univ Manitoba, Inflammatory Bowel Dis Clin & Res Ctr, Winnipeg, MB, Canada

[11] Univ Maryland, Sch Med, Inflammatory Bowel Dis Program, Baltimore, MD USA

[12] Yokohama Municipal Citizens Hosp, Dept Clin Res, Yokohama, Kanagawa, Japan

[13] Yokohama Municipal Citizens Hosp, Dept Inflammatory Bowel Dis, Yokohama, Kanagawa, Japan

[14] Henry Ford Hlth Syst, Dept Gastroenterol, Detroit, MI USA

[15] Univ Calif Los Angeles, Cedars Sinai Med Ctr, Los Angeles, CA 90048 USA

[16] Allegheny Hlth Network, Div Colon & Rectal Surg, Pittsburgh, PA USA

[17] Univ Hosp Leuven, Dept Abdominal Surg, Leuven, Belgium

[18] Brown Univ, Alpert Med Sch, Providence, RI 02912 USA

[19] Miriam Hosp, Gastroenterol Associates, Providence, RI 02906 USA

[20] Mayo Clin Florida, Div Gastroenterol & Hepatol, Jacksonville, FL USA

[21] Tel Aviv Univ, Tel Aviv Sourasky Med Ctr, Dept Gastroenterol, Tel Aviv, Israel

[22] Tel Aviv Univ, Fac Med, Tel Aviv, Israel

[23] Univ Florida, Dept Pathol Immunol & Lab Med, Gainesville, FL USA

[24] Goryeb Childrens Hosp, Atlantic Hlth, Dept Pediat Gastroenterol, Morristown, NJ USA

[25] New York Univ Langone Hlth, Div Gastroenterol, New York, NY USA

[26] New York Presbytarian Hosp, Weill Cornell Med, Div Gastroenterol & Hepatol, Jill Roberts Ctr IBD, New York, NY USA

[27] Vanderbilt Univ, Med Ctr, Dept Gastroenterol, Nashville, TN USA

[28] Catholic Univ Parana, Outpatients Clin, Curitiba, Parana, Brazil

[29] Cleveland Clin, Dept Gastroenterol Hepatol & Nutr, Cleveland, OH 44106 USA

[30] Houston Methodist, Houston, TX USA

[31] Weill Cornell Med Coll, Houston, TX USA

[32] Hillingdon Hosp, Dept Gastroenterol & Hepatol, Uxbridge, Middx, England

[33] Western Univ, Div Gastroenterol, Dept Med, London, ON, Canada

[34] Mt Sinai Hosp, Icahn Sch Med, Dept Gastroenterol, New York, NY 10029 USA

[35] Univ Hosp Ctr Dr Dragisa Misovic, IBD Clin Ctr, Belgrade, Serbia

[36] Columbia Univ, Irving Med Ctr, Morgan Stanley Childrens Hosp, Dept Pediat, New York, NY USA

[37] Univ Hosp Leuven, Dept Gastroenterol, Leuven, Belgium

[38] Univ Calif San Diego, Dept Gastroenterol, San Diego, CA 92103 USA

[39] Mt Sinai Hosp, Ctr Inflammatory Bowel Dis, Toronto, ON, Canada

来源：

LANCET GASTROENTEROLOGY & HEPATOLOGY | 2022年 / 7卷 / 01期

关键词：

CLOSTRIDIUM-DIFFICILE INFECTION; CHRONIC REFRACTORY POUCHITIS; ULCERATIVE-COLITIS PATIENTS; PRIMARY SCLEROSING CHOLANGITIS; LONG-TERM OUTCOMES; ANAL ANASTOMOSIS; RESTORATIVE PROCTOCOLECTOMY; ILEOANAL POUCH; BOWEL-DISEASE; DOUBLE-BLIND;

D O I：

10.1016/S2468-1253(21)00214-4

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Pouchitis, Crohn's disease of the pouch, cuffitis, polyps, and extraintestinal manifestations of inflammatory bowel disease are common inflammatory disorders of the ileal pouch. Acute pouchitis is treated with oral antibiotics and chronic pouchitis often requires anti-inflammatory therapy, induding the use of biologics. Aetiological factors for secondary pouchitis should be evaluated and managed accordingly. Crohn's disease of the pouch is usually treated with biologics and its stricturing and fistulising complications can be treated with endoscopy or surgery. The underlying cause of cuffitis determines treatment strategies. Endoscopic polypectomy is recommended for large, symptomatic inflammatory polyps and polyps in the cuff. The management principles of extraintestinal manifestations of inflammatory bowel disease in patients with pouches are similar to those in patients without pouches.

引用

页码：69 / 95

页数：27

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