Natural Product Synthesis by Intramolecular Alkylidene Carbene C-H Insertion

被引：1
|
作者：
Taber, Douglass F. [1 ]
机构：
[1] Univ Delaware, Dept Chem & Biochem, Newark, DE 19716 USA
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2022年 / 2022卷 / 10期
关键词：
C-H Activation; Cyclization; Natural products; Synthetic methods; FORMAL SYNTHESIS; UNSATURATED CARBENES; STEREOCONTROLLED SYNTHESIS; CONSTRUCTION; GENERATION; STEREOCHEMISTRY;
D O I：
10.1002/ejoc.202200032
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Direct functionalization of unactivated C-H bonds is of increasing importance in organic synthesis. Of the many methods that have been developed, intramolecular alkylidene C-H insertion, proceeding with retention of absolute configuration, is among the most versatile. This Review explores all examples of the use of intramolecular alkylidene C-H insertion in natural product synthesis.
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页数：9
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