Citalopram plus reboxetine in treatment-resistant obsessive-compulsive disorder

被引：7
|
作者：
Fontenelle, LF
Mendlowicz, MV
Miguel, EC
Versiani, M
机构：
[1] IPUB UFRJ, Inst Psychiat, Anxiety & Depress Res Program, Rio De Janeiro, Brazil
[2] IPUB UFRJ, Inst Psychiat, Ethics & Forens Psychiat Res Program, Rio De Janeiro, Brazil
[3] UFF, MSM, Dept Psychiat & Mental Hlth, Niteroi, RJ, Brazil
[4] USP, Sch Med, Obsess Compuls Spectrum Disorders Clin PROTOG, Dept Psychiat, BR-09500900 Sao Paulo, Brazil
来源：
WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY | 2005年 / 6卷 / 01期
关键词：
obsessive-compulsive disorder; citalopram; reboxetine;
D O I：
10.1080/15622970510029740
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
While serotonin reuptake inhibitors (SRIs) are the first-line treatment of obsessive-compulsive disorder (OCD), as many as 40-60% of patients fail to respond to adequate trials with these drugs. In this study, we describe the case of a patient with an SRI-resistant OCD who was successfully treated with a combination of citalopram (a selective SRI) and reboxetine (a selective noradrenaline reuptake inhibitor (SNRI)). This report suggests that future studies accessing the efficacy of the SRI-SNRI combination in treatment resistant OCD are needed.
引用
收藏
页码：57 / 59
页数：3
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