Analysis of amino acids network based on mutation and base positions

被引:2
|
作者
Ali, Tazid [1 ]
Borah, Chandra [1 ]
机构
[1] Dibrugarh Univ, Dept Math, Dibrugarh 786004, Assam, India
来源
GENE REPORTS | 2021年 / 24卷
关键词
Genetic code; Amino acid; Graph; Distance matrix; Centrality measure; Clustering coefficient; GENETIC-CODE; CENTRALITY; TABLE;
D O I
10.1016/j.genrep.2021.101291
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Analysis of the amino acids network is quite relevant for the study of multiple physicochemical amino acids characteristics. The inherent significance of base locations in a codon with chemical varieties of bases, Purine and Pyrimidine, plays the central role in the genetic code analysis. Weighing the transition and transversion mutation of codons and the role of base locations, we have developed a Distance Matrix and subsequently obtained an Amino Acids Network. We have investigated the evolutionary features of amino acids in protein synthesis in this network. For a comparative analysis regarding amino acids, we have examined numerous Centrality measures and explored Correlation Coefficients checking the Assortativity of the network. Also, as Network Parameters, we have analyzed the Clustering Coefficient, Degree Distribution, and Skewness.
引用
收藏
页数:7
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