Targeted Gene Repair Facilitated by Peptide Nucleic Acids (PNA)

被引:26
|
作者
Nielsen, Peter E. [1 ,2 ]
机构
[1] Univ Copenhagen, Panum Inst, Fac Hlth Sci, Dept Cellular & Mol Med, DK-2200 Copenhagen N, Denmark
[2] Univ Copenhagen, Fac Pharmaceut Sci, Dept Med Chem, DK-2100 Copenhagen, Denmark
关键词
DNA recognition; nucleic acids; peptide nucleic acids; recombination; targeted gene repair; ZINC-FINGER NUCLEASES; INTERSTRAND CROSS-LINKS; DOUBLE-DUPLEX INVASION; DOUBLE-STRANDED DNA; GAMMA-PNAS; RECOMBINATION; SPECIFICITY; THALASSEMIA; MUTATION; THERAPY;
D O I
10.1002/cbic.201000346
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页码:2073 / 2076
页数:4
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