A Two-Year Surveillance of 2009 Pandemic Influenza A (H1N1) in Guangzhou, China: From Pandemic to Seasonal Influenza?

被引：11

作者：

Li, Tiegang ^{[1
]}

Fu, Chuanxi ^{[1
]}

Di, Biao ^{[1
]}

Wu, Jibin ^{[1
]}

Yang, Zhicong ^{[1
]}

Wang, Yulin ^{[1
]}

Li, Meixia ^{[1
]}

Lu, Jianyun ^{[1
]}

Chen, Yiyun ^{[1
]}

Lu, Enjie ^{[1
]}

Geng, Jinmei ^{[1
]}

Hu, Wensui ^{[1
]}

Dong, Zhiqiang ^{[1
]}

Li, Meng-feng ^{[2
,3
]}

Zheng, Bo-Jian ^{[4
]}

Cao, Kai-yuan ^{[2
,3
]}

Wang, Ming ^{[1
]}

机构：

[1] Guangzhou Ctr Dis Control & Prevent, Guangzhou, Guangdong, Peoples R China

[2] Sun Yat Sen Univ, Sch Med, Dept Microbiol, Guangzhou 510275, Guangdong, Peoples R China

[3] Sun Yat Sen Univ, Minist Educ, Key Lab Trop Dis Control, Guangzhou 510275, Guangdong, Peoples R China

[4] Univ Hong Kong, Hong Kong, Hong Kong, Peoples R China

来源：

PLOS ONE | 2011年 / 6卷 / 11期

关键词：

UNITED-STATES; VIRUS; ENGLAND;

D O I：

10.1371/journal.pone.0028027

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In this two-years surveillance of 2009 pandemic influenza A (H1N1) (pH1N1) in Guangzhou, China, we reported here that the scale and duration of pH1N1 outbreaks, severe disease and fatality rates of pH1N1 patients were significantly lower or shorter in the second epidemic year (May 2010-April 2011) than those in the first epidemic year (May 2009-April 2010) (P<0.05), but similar to those of seasonal influenza (P>0.05). Similar to seasonal influenza, pre-existing chronic pulmonary diseases was a risk factor associated with fatal cases of pH1N1 influenza. Different from seasonal influenza, which occurred in spring/summer seasons annually, pH1N1 influenza mainly occurred in autumn/winter seasons in the first epidemic year, but prolonged to winter/spring season in the second epidemic year. The information suggests a tendency that the epidemics of pH1N1 influenza may probably further shift to spring/summer seasons and become a predominant subtype of seasonal influenza in coming years in Guangzhou, China.

引用

页数：5

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