hsa_circ_0072389, hsa_circ_0072386, hsa_circ_0008621, hsa_circ_0072387, and hsa_circ_0072391 aggravate glioma via miR-338-5p/IKBIP

被引:0
|
作者
Liang, Jian [1 ]
Li, Xing [3 ]
Xu, Jian [2 ]
Cai, Guang-Mou [1 ]
Cao, Jian-Xuan [1 ]
Zhang, Bo [1 ]
机构
[1] Jinan Univ, Clin Med Coll 2, Shenzhen Peoples Hosp, Shenzhen, Peoples R China
[2] Jinan Univ, Dept Hematol, Shenzhen Peoples Hosp, Clin Med Coll 2, Shenzhen, Peoples R China
[3] Southern Univ Sci & Technol, Sch Med, Shenzhen, Peoples R China
来源
AGING-US | 2021年 / 13卷 / 23期
关键词
miR-338-5p; circRNA; IKBIP; ceRNA; glioma; PROLIFERATION; EXPRESSION; MIGRATION; INVASION; CELLS;
D O I
暂无
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Glioma is a primary intracranial tumor with high morbidity and mortality. We acquired miR-338-5p, which suppresses the development of glioma, from the GEO and CGGA databases. In addition, we predicted that hsa_circ_0072389, hsa_circ_0072386, hsa_circ_0008621, hsa_circ_0072387, and hsa_circ_0072391 could relieve the silencing of IKBIP by miR-338-5p. By analyzing genes related to IKBIP expression, possible pathways affecting glioma were identified. This study provides new ideas for investigating multiple circRNAs in ceRNAs.
引用
收藏
页码:25213 / 25240
页数:28
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