hsa_circ_0072389, hsa_circ_0072386, hsa_circ_0008621, hsa_circ_0072387, and hsa_circ_0072391 aggravate glioma via miR-338-5p/IKBIP

被引：0

作者：

Liang, Jian ^{[1
]}

Li, Xing ^{[3
]}

Xu, Jian ^{[2
]}

Cai, Guang-Mou ^{[1
]}

Cao, Jian-Xuan ^{[1
]}

Zhang, Bo ^{[1
]}

机构：

[1] Jinan Univ, Clin Med Coll 2, Shenzhen Peoples Hosp, Shenzhen, Peoples R China

[2] Jinan Univ, Dept Hematol, Shenzhen Peoples Hosp, Clin Med Coll 2, Shenzhen, Peoples R China

[3] Southern Univ Sci & Technol, Sch Med, Shenzhen, Peoples R China

来源：

AGING-US | 2021年 / 13卷 / 23期

关键词：

miR-338-5p; circRNA; IKBIP; ceRNA; glioma; PROLIFERATION; EXPRESSION; MIGRATION; INVASION; CELLS;

D O I：

暂无

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Glioma is a primary intracranial tumor with high morbidity and mortality. We acquired miR-338-5p, which suppresses the development of glioma, from the GEO and CGGA databases. In addition, we predicted that hsa_circ_0072389, hsa_circ_0072386, hsa_circ_0008621, hsa_circ_0072387, and hsa_circ_0072391 could relieve the silencing of IKBIP by miR-338-5p. By analyzing genes related to IKBIP expression, possible pathways affecting glioma were identified. This study provides new ideas for investigating multiple circRNAs in ceRNAs.

引用

页码：25213 / 25240

页数：28

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