Fty720, Sphingosine 1-phosphate Receptor Modulator, Selectively Radioprotects Hippocampal Neural Stem Cells

被引:0
|
作者
Stessin, A. [1 ]
Wernicke, A. G. [1 ]
Parashar, B. [1 ]
Sabbas, A. M. [1 ]
Kulidzhanov, F. G. [1 ]
Nori, D. [1 ]
机构
[1] Weill Cornell Med Coll, New York, NY USA
关键词
D O I
10.1016/j.ijrobp.2012.07.182
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:S108 / S108
页数:1
相关论文
共 50 条
  • [31] The sphingosine 1-phosphate receptor agonist FTY720 is neuroprotective after cuprizone-induced CNS demyelination
    Slowik, A.
    Schmidt, T.
    Beyer, C.
    Amor, S.
    Clarner, T.
    Kipp, M.
    BRITISH JOURNAL OF PHARMACOLOGY, 2015, 172 (01) : 80 - 92
  • [32] The Sphingosine-1-Phosphate Receptor Modulator, FTY720, Reverses Diastolic Dysfunction and Hypertrophy in Hypertrophic Cardiomyopathy
    Ryba, David M.
    Warren, Chad M.
    Karam, Chehade N.
    Dovis, Robert T., III
    Chowdhury, Shamim A. K.
    Alvarez, Manuel G.
    Wieczorek, David F.
    Solaro, R. John
    Wolska, Beata M.
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2017, 112 : 156 - 157
  • [33] The sphingosine 1-phosphate receptor modulator FTY720 prevents iodide-induced autoimmune thyroiditis in non-obese diabetic mice
    Morohoshi, Kazuki
    Osone, Michiko
    Yoshida, Katsumi
    Nakagawa, Yoshinori
    Hoshikawa, Saeko
    Ozaki, Hiroshi
    Takahashi, Yurie
    Ito, Sadayoshi
    Mori, Kouki
    AUTOIMMUNITY, 2011, 44 (06) : 490 - 495
  • [34] The mode of action of Fingolimod (FTY720), an oral sphingosine 1-phosphate receptor modulator that is highly effective in human multiple sclerosis (Phase II)
    Brinkmann, V.
    Metzler, B.
    Matloubian, M.
    Mitruecker, H.
    MULTIPLE SCLEROSIS, 2006, 12 : S100 - S100
  • [35] Fingolimod (FTY720), sphingosine 1-phosphate receptor modulator, shows superior efficacy as compared with interferon-β in mouse experimental autoimmune encephalomyelitis
    Chiba, Kenji
    Kataoka, Hirotoshi
    Seki, Noriyasu
    Shimano, Kyoko
    Koyama, Mamoru
    Fukunari, Atsushi
    Sugahara, Kunio
    Sugita, Takahisa
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2011, 11 (03) : 366 - 372
  • [36] Immunosuppressive activity of FTY720, sphingosine 1-phosphate receptor agonist: II. Effect of FTY720 and FTY720-phosphate on host-versus-graft and graft-versus-host reaction in mice
    Kataoka, H
    Ohtsuki, M
    Shimano, K
    Mochizuki, S
    Oshita, K
    Murata, M
    Sugahara, K
    Sato, N
    Hoshino, Y
    Chiba, K
    TRANSPLANTATION PROCEEDINGS, 2005, 37 (01) : 107 - 109
  • [37] The sphingosine 1-phosphate receptor (S1PR) agonist FTY720 inhibits lymphatic transendothelial migration.
    Lal, Girdhari
    Zhang, Nan
    Ledgerwood, Levi
    Esses, Steven J.
    Bromberg, Jonathan S.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2007, 7 : 154 - 154
  • [38] The Sphingosine 1-Phosphate Receptor Agonist FTY720 Potently Inhibits Regulatory T Cell Proliferation In Vitro and In Vivo
    Wolf, Anna Maria
    Eller, Kathrin
    Zeiser, Robert
    Duerr, Christoph
    Gerlach, Ulrike V.
    Sixt, Michael
    Markut, Lydia
    Gastl, Guenther
    Rosenkranz, Alexander R.
    Wolf, Dominik
    JOURNAL OF IMMUNOLOGY, 2009, 183 (06): : 3751 - 3760
  • [39] Absorption and Disposition of the Sphingosine 1-Phosphate Receptor Modulator Fingolimod (FTY720) in Healthy Volunteers: A Case of Xenobiotic Biotransformation Following Endogenous Metabolic Pathways
    Zollinger, Markus
    Gschwind, Hans-Peter
    Jin, Yi
    Sayer, Claudia
    Zecri, Frederic
    Hartmann, Stefan
    DRUG METABOLISM AND DISPOSITION, 2011, 39 (02) : 199 - 207
  • [40] Lusitropic and anti-hypertrophic effects of the sphingosine-1-phosphate receptor modulator, FTY720, in hypertrophic cardiomyopathy
    Ryba, D. M.
    Warren, C. M.
    Karam, C. N.
    Davis, R. T., III
    Chowdhury, S. A. K.
    Alvarez, M. G.
    Wieczorek, D. F.
    Solaro, R. J.
    Wolska, B. M.
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2017, 109 : 12 - 12