The Return of Delayed-Type Hypersensitivity Skin Testing for Coccidioidomycosis

被引：32
|
作者：
Wack, Elizabeth E. [1 ]
Ampel, Neil M. [2 ,3 ]
Sunenshine, Rebecca H. [4 ,5 ]
Galgiani, John N. [1 ,2 ]
机构：
[1] Valley Fever Ctr Excellence, Tucson, AZ USA
[2] Univ Arizona, Coll Med, Tucson, AZ 85724 USA
[3] Southern Arizona Vet Affairs Hlth Care Syst, Tucson, AZ USA
[4] Maricopa Cty Dept Hlth, Phoenix, AZ USA
[5] Ctr Dis Control & Prevent, Atlanta, GA USA
来源：
CLINICAL INFECTIOUS DISEASES | 2015年 / 61卷 / 05期
关键词：
coccidioidomycosis; delayed type hypersensitivity; skin test; cellular immunity; diagnostic test; CHEMICALLY-DEFINED MEDIUM; DERMAL SENSITIVITY; WASHINGTON-STATE; IMMUNE-RESPONSE; IMMITIS; SPHERULIN; PNEUMONIA; OUTBREAK; ARIZONA; USA;
D O I：
10.1093/cid/civ388
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
A skin test that detects dermal hypersensitivity in persons with past infection with Coccidioides species is again available for clinical use. Nearly all of the clinical studies with similar materials were published prior to the 1990s, and as a result, many practicing physicians will be unfamiliar with how skin testing for coccidioidomycosis might be useful in patient management or as a research tool. We review clinical and epidemiological studies with past skin test antigens, the composition of past and current skin test preparations with particular attention to differences in the preservatives, and how the current preparation could be used today.
引用
收藏
页码：787 / 791
页数：5
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