Computational analyses of TBC protein family in eukaryotes

被引：8
|
作者：
Gao, Xinjiao
Jin, Changjiang
Xue, Yu [1 ]
Yao, Xuebiao
机构：
[1] Hefei Natl Lab Phys Sci Microscale, Lab Cellular Dynam, Hefei 230027, Anhui, Peoples R China
[2] Univ Sci & Technol China, Hefei 230027, Anhui, Peoples R China
来源：
PROTEIN AND PEPTIDE LETTERS | 2008年 / 15卷 / 05期
关键词：
TBC domain; phylogenetic tree; USP6; polarized exocytosis; cell cycle; cytokinesis;
D O I：
10.2174/092986608784567483
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Tre-2/Bub2/Cdc16 domain-containing proteins (TBC proteins) participate in wide range cellular processes. With computational approaches, 137 non-redundant TBC proteins from five model organisms were identified and classified into 13 subfamilies base on molecular evolutionary tree. This phylogenetic analysis provides useful functional annotation of newly-identified TBC proteins and guides for further experimentation.
引用
收藏
页码：505 / 509
页数：5
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