Purpose: The aim of this study was to evaluate the obstetric outcomes of women with rheumatoid arthritis (RA) Materials and Methods: This retrospective study consisted of 39 women with RA. Patients were evaluated in terms of seropositivity, having disease >5 years or not and use of any medication. Results: Rate of preterm delivery and intrauterine growth retardation was 33.3% and 21.2%, respectively. Comparisons between seropositive and seronegative women did not show any significant difference. Having disease more or less than 5 years did not show any significant difference in terms of obstetric outcomes. Women with a coexisting disease had a similar rate of miscarriage rate compared to remainders (16.6% vs 14.8%). Women followed up without any medication has also higher rates of miscarriage despite lack of statistical significance. Conclusion: Pregnancies of women with RA must be considered as high risk due to increased rates of adverse pregnancy outcomes such as preterm delivery and intrauterine growth retardation.
机构:
Univ Manchester, Manchester Acad Hlth Sci Ctr, Arthrit Res UK Ctr Epidemiol, Manchester, Lancs, EnglandUniv Manchester, Manchester Acad Hlth Sci Ctr, Arthrit Res UK Ctr Epidemiol, Manchester, Lancs, England
Birmingham, Lucy
Watson, Kath D.
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Univ Manchester, Manchester Acad Hlth Sci Ctr, Arthrit Res UK Ctr Epidemiol, Manchester, Lancs, EnglandUniv Manchester, Manchester Acad Hlth Sci Ctr, Arthrit Res UK Ctr Epidemiol, Manchester, Lancs, England
Watson, Kath D.
Kearsley-Fleet, Lianne
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Univ Manchester, Manchester Acad Hlth Sci Ctr, Arthrit Res UK Ctr Epidemiol, Manchester, Lancs, EnglandUniv Manchester, Manchester Acad Hlth Sci Ctr, Arthrit Res UK Ctr Epidemiol, Manchester, Lancs, England
Kearsley-Fleet, Lianne
Symmons, Deborah P.
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Univ Manchester, Manchester Acad Hlth Sci Ctr, Arthrit Res UK Ctr Epidemiol, Manchester, Lancs, England
Cent Manchester NHS Fdn Trust, Manchester Acad Hlth Sci, Manchester Musculoskeletal Biomed Res Unit, Natl Inst Hlth Res, Manchester, Lancs, EnglandUniv Manchester, Manchester Acad Hlth Sci Ctr, Arthrit Res UK Ctr Epidemiol, Manchester, Lancs, England