Pregnancy outcomes of patients with rheumatoid arthritis

被引:0
|
作者
Fadiloglu, Erdem [1 ]
Unal, Canan [1 ]
Tanacan, Atakan [1 ]
Beksac, M. Sinan [1 ]
机构
[1] Hacettepe Univ, Dept Obstet & Gynecol, Div Perinatol, Ankara, Turkey
来源
CUKUROVA MEDICAL JOURNAL | 2020年 / 45卷 / 02期
关键词
Pregnancy; rheumatoid arthritis; obstetric outcome; miscarriage; DISEASE-ACTIVITY; PRETERM BIRTH; GROWTH;
D O I
10.17826/cumj.664235
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose: The aim of this study was to evaluate the obstetric outcomes of women with rheumatoid arthritis (RA) Materials and Methods: This retrospective study consisted of 39 women with RA. Patients were evaluated in terms of seropositivity, having disease >5 years or not and use of any medication. Results: Rate of preterm delivery and intrauterine growth retardation was 33.3% and 21.2%, respectively. Comparisons between seropositive and seronegative women did not show any significant difference. Having disease more or less than 5 years did not show any significant difference in terms of obstetric outcomes. Women with a coexisting disease had a similar rate of miscarriage rate compared to remainders (16.6% vs 14.8%). Women followed up without any medication has also higher rates of miscarriage despite lack of statistical significance. Conclusion: Pregnancies of women with RA must be considered as high risk due to increased rates of adverse pregnancy outcomes such as preterm delivery and intrauterine growth retardation.
引用
收藏
页码:518 / 525
页数:8
相关论文
共 50 条
  • [1] PREGNANCY OUTCOMES IN RHEUMATOID ARTHRITIS PATIENTS TREATED WITH TOCILIZUMAB
    Ishikawa, H.
    Kaneko, A.
    Hattori, Y.
    Takahashi, N.
    Kida, D.
    Sato, T.
    Osawa, Y.
    ANNALS OF THE RHEUMATIC DISEASES, 2014, 73 : 501 - 502
  • [2] Pregnancy Outcomes in Patients with Rheumatoid Arthritis and Systemic Lupus Erythematosus
    Matianova, Elena Vladimirovna
    Kosheleva, Nadejda Mihailovna
    Fedorova, Ekaterina Vasilievna
    Alekberova, Zemfira Sadulaevna
    Nasonov, Evgeniy Lvovich
    CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2014, 32 (04) : S98 - S99
  • [3] Pregnancy outcomes in women with rheumatoid arthritis
    Friden, Cecilia
    Glass, Roberta
    Cui, Jing
    Shadick, Nancy
    Iversen, Maura D.
    ARTHRITIS AND RHEUMATISM, 2008, 58 (09): : S437 - S438
  • [4] Pregnancy in rheumatoid arthritis patients
    Olas, J.
    Ludwin, A.
    ANNALS OF THE RHEUMATIC DISEASES, 2007, 66 : 674 - 674
  • [5] PREGNANCY OUTCOMES IN WOMEN WITH AND WITHOUT RHEUMATOID ARTHRITIS
    Clowse, M. E. B.
    McDaniel, G.
    Eudy, A. M.
    ANNALS OF THE RHEUMATIC DISEASES, 2017, 76 : 813 - 814
  • [6] Pregnancy outcomes in patients with rheumatoid arthritis who discontinue methotrexate treatment to conceive
    Nagafuchi, Hiroko
    Goto, Yutaka
    Kiyokawa, Tomofumi
    Ooka, Seido
    Kawahata, Kimito
    CLINICAL RHEUMATOLOGY, 2022, 41 (03) : 669 - 675
  • [7] PREGNANCIES IN PATIENTS WITH RHEUMATOID ARTHRITIS: TREATMENT DECISIONS, COURSE OF THE DISEASE, AND PREGNANCY OUTCOMES
    Strangfeld, A.
    Pattloch, D.
    Spilka, M.
    Manger, B.
    Krummel-Lorenz, B.
    Graessler, A.
    Listing, J.
    Zink, A.
    ANNALS OF THE RHEUMATIC DISEASES, 2015, 74 : 70 - +
  • [8] Pregnancy Outcomes in Patients with Rheumatoid Arthritis Treated with Abatacept - Review of a Safety Database
    Yu, H.
    Angelini, K.
    Dominique, A.
    Simon, T. A.
    ARTHRITIS & RHEUMATOLOGY, 2016, 68
  • [9] Pregnancy outcomes in patients with rheumatoid arthritis who discontinue methotrexate treatment to conceive
    Hiroko Nagafuchi
    Yutaka Goto
    Tomofumi Kiyokawa
    Seido Ooka
    Kimito Kawahata
    Clinical Rheumatology, 2022, 41 : 669 - 675
  • [10] Adverse Pregnancy Outcomes and Risk of Subsequent Rheumatoid Arthritis
    Ma, Kimberly K.
    Guthrie, Katherine A.
    Nelson, J. Lee
    Dugowson, Carin E.
    Gammill, Hilary S.
    REPRODUCTIVE SCIENCES, 2012, 19 (S3) : 133A - 134A