Dynamics of conduction blocks in a model of paced cardiac tissue

被引：22
|
作者：
Henry, H [1 ]
Rappel, WJ [1 ]
机构：
[1] Univ Calif San Diego, Ctr Theoret Biol Phys, La Jolla, CA 92093 USA
来源：
PHYSICAL REVIEW E | 2005年 / 71卷 / 05期
关键词：
D O I：
10.1103/PhysRevE.71.051911
中图分类号：
O35 [流体力学]; O53 [等离子体物理学];
学科分类号：
070204 ; 080103 ; 080704 ;
摘要：
We study numerically the dynamics of conduction blocks using a detailed electrophysiological model. We find that this dynamics depends critically on the size of the paced region. Small pacing regions lead to stationary conduction blocks while larger pacing regions can lead to conduction blocks that travel periodically towards the pacing region. We show that this size-dependence dynamics can lead to a novel arrhythmogenic mechanism. Furthermore, we show that the essential phenomena can be captured in a much simpler coupled-map model.
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页数：7
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