Bioassay-guided isolation of antimicrobial benzopyrans and phloroglucinol derivatives from Hypericum species

被引：27
|
作者：
Dall'Agnol, R [1 ]
Ferraz, A [1 ]
Bernardi, AP [1 ]
Albring, D [1 ]
Nör, C [1 ]
Schapoval, EES [1 ]
von Poser, GL [1 ]
机构：
[1] Univ Fed Rio Grande do Sul, Fac Farm, Programa Pos Grad Ciencias Farmaceut, BR-90610000 Porto Alegre, RS, Brazil
来源：
PHYTOTHERAPY RESEARCH | 2005年 / 19卷 / 04期
关键词：
Staphylococcus aureus; bioautography; antibacterial; polyphenolic compounds; natural products;
D O I：
10.1002/ptr.1546
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Recently the crude methanol extracts of six Hypericum species were analysed against a panel of microorganisms and it was found that H. caprifoliatum Cham. & Schlecht., H. myrianthum Cham. & Schlecht. and H. polyanthemum Klotzsch ex Reichardt were the most active. This paper reports the activity of the hexane, chloroform and methanol fractions of these plants as well as the activity of some isolated compounds against Staphylococcus aureus determined by bioautographic procedures. Copyright (c) 2005 John Wiley & Sons, Ltd.
引用
收藏
页码：291 / 293
页数：3
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