Rapid itch improvement with upadacitinib with or without concomitant topical corticosteroids (TCS) in moderate-to-severe atopic dermatitis (AD): Results from 3 phase 3 studies (Measure Up 1, Measure Up 2, and AD Up)

被引:0
|
作者
Blauvelt, Andrew [1 ]
Ardern-Jones, Michael R. [2 ,3 ]
Bieber, Thomas [4 ]
Hong, Chih-Ho [5 ,6 ,7 ]
Chu, Chia-Yu [8 ,9 ]
Liu, Meng [10 ]
Yang, Yang [10 ]
Ladizinski, Barry [10 ]
Teixeira, Henrique D. [10 ]
Calimlim, Brian M. [10 ]
Thyssen, Jacob P. [11 ]
机构
[1] Oregon Med Res Ctr, Portland, OR USA
[2] Univ Hosp Southampton NHS Fdn Trust, Southampton Gen Hosp, Dept Dermatol, Southampton, Hants, England
[3] Univ Southampton, Clin Expt Sci, Fac Med, Southampton, Hants, England
[4] Univ Bonn, Dept Dermatol & Allergy, Bonn, Germany
[5] Dr Chih ho Hong Med Inc, Surrey, BC, Canada
[6] Univ British Columbia, Dept Dermatol & Skin Sci, Vancouver, BC, Canada
[7] Prob Med Res, Surrey, BC, Canada
[8] Natl Taiwan Univ Hosp, Dept Dermatol, Taipei, Taiwan
[9] Natl Taiwan Univ, Coll Med, Taipei, Taiwan
[10] AbbVie Inc, N Chicago, IL USA
[11] Herlev & Gentofte Hosp, Dept Dermatol & Allergy, Hellerup, Denmark
关键词
D O I
暂无
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
28032
引用
收藏
页码:AB171 / AB171
页数:1
相关论文
共 50 条
  • [31] ABSOLUTE EASI TARGET IN MODERATE-TO-SEVERE ATOPIC DERMATITIS: ANALYSIS OF DATA FROM THE MEASURE UP 1 AND 2 STUDIES
    Prajapatil, Vimal
    Simpson, Eric L.
    Thyssen, Jacob P.
    Chovatiya, Raj
    Lane, Michael
    Teixeira, Henrique
    Calimlim, Brian
    Silverberg, Jonathan I.
    ACTA DERMATO-VENEREOLOGICA, 2022, 102 : 33 - 33
  • [32] Effects of upadacitinib on patient-reported symptoms of atopic dermatitis: Atopic Dermatitis Symptom Scale (ADerm-SS) results from two pivotal phase 3 studies (MEASURE UP 1 and MEASURE UP 2)
    Silverberg, Jonathan I.
    Thyssen, Jacob P.
    Rosmarin, David
    Pink, Andrew E.
    Calimlim, Brian M.
    Teixeira, Henrique D.
    Hu, Xiaofei
    Yang, Yang
    Thaci, Diamant
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2021, 85 (03) : AB7 - AB7
  • [33] Efficacy and Safety of Upadacitinib in Patients With Moderate to Severe Atopic Dermatitis Analysis of Follow-up Data From the Measure Up 1 and Measure Up 2 Randomized Clinical Trials
    Simpson, Eric L.
    Papp, Kim A.
    Blauvelt, Andrew
    Chu, Chia-Yu
    Hong, H. Chih-Ho
    Katoh, Norito
    Calimlim, Brian M.
    Thyssen, Jacob P.
    Chiou, Albert S.
    Bissonnette, Robert
    Gold, Linda F. Stein
    Wegzyn, Colleen
    Hu, Xiaofei
    Liu, Meng
    Liu, John
    Tenorio, Allan R.
    Chu, Alvina D.
    Guttman-Yassky, Emma
    JAMA DERMATOLOGY, 2022, 158 (04) : 404 - 413
  • [34] Safety and efficacy of upadacitinib monotherapy in adolescents and adults with moderate-to-severe atopic dermatitis: results from two pivotal, phase III, randomized, double-blinded, monotherapy, placebo-controlled studies (Measure Up 1 and Measure Up 2)
    Guttman-Yassky, E.
    Teixeira, H. D.
    Simpson, E. L.
    Papp, K. A.
    Pangan, A. L.
    Blauvelt, A.
    Thaci, D.
    Chu, C. Y.
    Hong, H. C.
    Katoh, N.
    Paller, A. S.
    Calimlim, B.
    Gu, Y.
    Hu, X.
    Liu, M.
    Yang, Y.
    Tenorio, A. R.
    Chu, A. D.
    Irvine, A. D.
    BRITISH JOURNAL OF DERMATOLOGY, 2021, 184 (03) : E62 - E62
  • [35] Characterization of haematological and transaminase laboratory findings associated with upadacitinib use in moderate-to-severe atopic dermatitis: results of two phase III Trials (Measure Up 1 and 2)
    Silverberg, J. I.
    Gooderham, M. J.
    de Bruin-Weller, M. S.
    Papp, K. A.
    Aoki, V.
    Paller, A. S.
    Ofori, S.
    Tenorio, A. R.
    Liu, Y.
    Liu, J.
    Chovatiya, Raj
    BRITISH JOURNAL OF DERMATOLOGY, 2022, 186 (04) : E168 - E169
  • [36] Rapid skin clearance and itch improvement with upadacitinib versus dupilumab in adults with moderate-to-severe atopic dermatitis: results from a phase 3b head-to-head clinical trial (Heads Up)
    Simpson, Eric L.
    Costanzo, Antonio
    Prajapati, Vimal H.
    Calimlim, Brian M.
    Chu, Alvina D.
    Wu, Tianshuang
    Eyerich, Kilian
    BRITISH JOURNAL OF DERMATOLOGY, 2024, 190 : II30 - II31
  • [37] UPADACITINIB VERSUS DUPILUMAB IN ADULTS WITH MODERATE-TO-SEVERE ATOPIC DERMATITIS: ANALYSIS OF THE HEADS UP PHASE 3 TRIAL
    Blauvelt, Andrew
    Teixeira, Henrique D.
    Simpson, Eric L.
    Costanzo, Antonio
    De Bruin-Weller, Marjolein
    Barbarot, Sebastien
    Prajapati, Vimal H.
    Lio, Peter
    Hu, Xiaofei
    Wu, Tianshuang
    Liu, John
    Ladizinski, Barry
    Chu, Alvina D.
    Eyerich, Kilian
    ACTA DERMATO-VENEREOLOGICA, 2021, 101 : 62 - 62
  • [38] Improvement in patient global impression measures with upadacitinib with or without topical corticosteroids in moderate to severe atopic dermatitis: Results from placebo-controlled phase 3 studies
    Gooderham, M.
    Deleuran, M.
    Gold, L. S.
    Calimlim, B.
    Zeng, J.
    Takemoto, S.
    Raymundo, E.
    Weidinger, S.
    EXPERIMENTAL DERMATOLOGY, 2021, 30 : 16 - 17
  • [39] Early and Sustained Improvements in Symptoms and Quality of Life with Upadacitinib in Adults and Adolescents with Moderate-to-Severe Atopic Dermatitis: 52-Week Results from Two Phase III Randomized Clinical Trials (Measure Up 1 and Measure Up 2)
    Silverberg, Jonathan I.
    Gooderham, Melinda J.
    Paller, Amy S.
    Deleuran, Mette
    Bunick, Christopher G.
    Gold, Linda F. Stein
    Hijnen, Dirkjan
    Calimlim, Brian M.
    Lee, Wan-Ju
    Teixeira, Henrique D.
    Hu, Xiaofei
    Zhang, Shiyu
    Yang, Yang
    Grada, Ayman
    Platt, Andrew M.
    Thaci, Diamant
    AMERICAN JOURNAL OF CLINICAL DERMATOLOGY, 2024, 25 (03) : 485 - 496
  • [40] Early and Sustained Improvements in Symptoms and Quality of Life with Upadacitinib in Adults and Adolescents with Moderate-to-Severe Atopic Dermatitis: 52-Week Results from Two Phase III Randomized Clinical Trials (Measure Up 1 and Measure Up 2)
    Jonathan I. Silverberg
    Melinda J. Gooderham
    Amy S. Paller
    Mette Deleuran
    Christopher G. Bunick
    Linda F. Stein Gold
    DirkJan Hijnen
    Brian M. Calimlim
    Wan-Ju Lee
    Henrique D. Teixeira
    Xiaofei Hu
    Shiyu Zhang
    Yang Yang
    Ayman Grada
    Andrew M. Platt
    Diamant Thaçi
    American Journal of Clinical Dermatology, 2024, 25 : 485 - 496