An analysis of the in vitro metabolism of dextromethorphan by accurate mass spectrometry with stable-isotope labeled metabolite profiling and reaction phenotyping

被引：0
|
作者：
Barbara, Joanna E. [1 ]
Horrigan, Mark J. [1 ]
Yerino, Phyllis [1 ]
Kazmi, Faraz [1 ]
Toren, Paul C. [1 ]
Parkinson, Andrew [1 ]
机构：
[1] XenoTech LLC, Lenexa, KS 66219 USA
来源：
DRUG METABOLISM REVIEWS | 2009年 / 41卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
70
引用
收藏
页码：35 / 36
页数：2
相关论文
共 50 条
  • [31] Analysis of stable isotope labeled phenylalanine distribution in mice albumin using liquid chromatographyelectrospray ionization mass spectrometry.
    Lu, XM
    Carter, EA
    Lu, M
    Fischman, AJ
    Tompkins, RG
    HEPATOLOGY, 2002, 36 (04) : 440A - 440A
  • [32] Profiling of potential brassinosteroids in different tissues of rape flower by stable isotope labeling - liquid chromatography/mass spectrometry analysis
    Yu, Lei
    Ye, Tiantian
    Bai, Ya-Li
    Cai, Wen-Jing
    Ding, Jun
    Yuan, Bi-Feng
    Feng, Yu-Qi
    ANALYTICA CHIMICA ACTA, 2018, 1037 : 55 - 62
  • [33] i-RUBY: A novel software for quantitative analysis of highly accurate shotgun-proteomics liquid chromatography/tandem mass spectrometry data obtained without stable-isotope labeling of proteins
    Wada, Kazuya
    Ogiwara, Atsushi
    Nagasaka, Keiko
    Tanaka, Naoki
    Komatsu, Yasuhiko
    RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2011, 25 (07) : 960 - 968
  • [34] Stable isotope labeling-solid phase extraction-mass spectrometry analysis for profiling of thiols and aldehydes in beer
    Zheng, Shu-Jian
    Wang, Ya-Lan
    Liu, Ping
    Zhang, Zheng
    Yu, Lei
    Yuan, Bi-Feng
    Feng, Yu-Qi
    FOOD CHEMISTRY, 2017, 237 : 399 - 407
  • [35] Production and application of high quality stable isotope-labeled human immunoglobulin G1 for mass spectrometry analysis
    Phillip, Amsler
    Thierry, Wolf
    Christian, Lanshoeft
    Anja, Bettighofer
    Jochen, Eisfeld
    Thomas, Moenius
    Claudia, Probst
    Coralie, Etter
    Olivier, Heudi
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2017, 60 (03): : 160 - 167
  • [36] Probing dietary triacylglycerol metabolism and meibogenesis in mice: A stable isotope-labeled tracer liquid chromatography-tandem mass spectrometry study
    Butovich, Igor A.
    Yuksel, Seher
    Wilkerson, Amber
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2023, 299 (04)
  • [37] Syntheses of isotope-labeled and -unlabeled N-beta-naphthyliodoacetamide and application to quantitative analysis of peptides and proteins by stable isotope differential mass spectrometry
    Niwayama, Satomi
    Kurono, Sadamu
    Cho, Hanjoung
    Matsumoto, Hiroyuki
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 231
  • [38] STABLE-ISOTOPE DILUTION STUDIES OF AN INTACT PROTEIN USING HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY CHEMICAL-REACTION INTERFACE MASS-SPECTROMETRY
    OSBORN, BL
    ABRAMSON, FP
    ANALYTICAL BIOCHEMISTRY, 1995, 229 (02) : 347 - 350
  • [39] ANALYSIS OF 8-HYDROXY-2'-DEOXYGUANOSINE IN RAT URINE AND LIVER DNA BY STABLE-ISOTOPE DILUTION GAS-CHROMATOGRAPHY MASS-SPECTROMETRY
    TEIXEIRA, AJR
    FERREIRA, MR
    VANDIJK, WJ
    VANDEWERKEN, G
    DEJONG, APJM
    ANALYTICAL BIOCHEMISTRY, 1995, 226 (02) : 307 - 319
  • [40] Targeted lipidomics profiling of acute arsenic exposure in mice serum by on-line solid-phase extraction stable-isotope dilution liquid chromatography–tandem mass spectrometry
    Chao-Yu Chen
    Pinpin Lin
    Ming-Hsien Tsai
    Hui-Ling Lee
    Archives of Toxicology, 2017, 91 : 3079 - 3091
12345