Mycobacterium bovis infection in a horse with granulomatous enterocolitis

被引:7
|
作者
Sarradell, Javier E. [1 ]
Alvarez, Julio [2 ]
Biscia, Mariana [1 ]
Zumarraga, Martin [4 ]
Wunschmann, Arno [3 ]
Armien, Anibal G. [3 ]
Perez, Andres M. [2 ]
机构
[1] Natl Univ Rosario, Fac Vet, Dept Gen & Syst Pathol, Casilda, Argentina
[2] Univ Minnesota, Coll Vet Med, Dept Vet Populat Med, St Paul, MN 55108 USA
[3] Univ Minnesota, Coll Vet Med, Vet Diagnost Lab, St Paul, MN 55108 USA
[4] Natl Agr Technol Inst INTA, Ctr Agron & Vet Sci, Inst Biotechnol, Buenos Aires, DF, Argentina
关键词
Argentina; horse; Mycobacterium bovis; tuberculosis; POLYMERASE-CHAIN-REACTION; LATIN-AMERICAN; TUBERCULOSIS; COUNTRIES; AVIUM; ARGENTINA; SHEEP;
D O I
10.1177/1040638715571359
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
A 2-year-old dappled Percheron horse had a wasting condition that did not respond to antibiotic treatments and ultimately resulted in death. Thickening of the wall of the large colon and enlargement of the mesenteric lymph nodes were observed at postmortem examination, along with the presence of pinpoint whitish foci in the liver. Microscopic examination of affected tissues revealed diffuse chronic granulomatous enterocolitis, granulomatous mesenteric lymphadenitis, and multifocal granulomatous hepatitis. The DNA extracted from paraffin-embedded intestinal and lymph node samples was analyzed using both a polymerase chain reaction (PCR) assay and PCR-restriction endonuclease analysis and demonstrated the presence of Mycobacterium bovis.
引用
收藏
页码:203 / 205
页数:3
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