Castleman's disease: An unusually young presentation resulting in delayed diagnosis of a neck mass

We present a case report of a two year old child with an enlarging neck mass over a two year period. Her work-up included blood investigations, radiological imaging and fine needle aspirations which were non-diagnostic. At age 4 she had excision of her neck mass and histopathologic examination revealed unicentric Castleman's disease. This is one of the youngest reported cases in the literature and highlights the need to include CD in the differential diagnosis of neck masses in young children. Castleman's disease (CD) is a rare disease of benign lymph node enlargement which most commonly occurs in adults. While the multi-centric variant is associated with HIV and HHV-8 infection, the aetiology of unicentric disease remains uncertain. (C) 2016 Elsevier Ireland Ltd. All rights reserved.