DNA damage response as biomarkers informing a precision medicine approach to bladder cancer: what are the next steps?

被引：0
|
作者：
Niglio, Scot [1 ]
Galsky, Matthew D. [1 ]
机构：
[1] Icahn Sch Med Mt Sinai, Tisch Canc Inst, Div Hematol Oncol, Dept Med, 1 Gustave L Levy Pl, New York, NY 10029 USA
来源：
EXPERT REVIEW OF PRECISION MEDICINE AND DRUG DEVELOPMENT | 2019年 / 4卷 / 01期
关键词：
Bladder cancer; urothelial cancer; DNA damage response; DDR; check point blockade; program cell death ligand 1; cytotoxic T-lymphocyte-associated protein 4; PD-L1; PD-1; CTLA4; ERCC2; REPAIR GENES; CHEMOTHERAPY; LANDSCAPE;
D O I：
10.1080/23808993.2019.1539621
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：7 / 9
页数：3
相关论文
共 50 条
  • [21] Sequencing of genes of drug response in tumor DNA and implications for precision medicine in cancer patients
    Nancy Gillis
    Amy S. Etheridge
    Sushant A. Patil
    D. Neil Hayes
    Michele C. Hayward
    J. Todd Auman
    Joel S. Parker
    Federico Innocenti
    [J]. The Pharmacogenomics Journal, 2023, 23 : 73 - 81
  • [22] Clinical Activity of Olaparib in Urothelial Bladder Cancer With DNA Damage Response Gene Mutations
    Sweis, Randy F.
    Heiss, Brian
    Segal, Jeremy
    Ritterhouse, Lauren
    Kadri, Sabah
    Churpek, Jane E.
    Allen, Kenisha
    Conway, Dawn
    Marinier, Carolyn
    Smith, Norm D.
    Pitroda, Sean P.
    Stadler, Walter M.
    [J]. JCO PRECISION ONCOLOGY, 2018, 2 : 1 - 7
  • [23] Biomarkers for Metastatic Castration-resistant Prostate Cancer (mCRPC): Yes or No? Predictive and Response Biomarkers Towards Precision Medicine in mCRPC
    Mateo, Joaquin
    [J]. EUROPEAN UROLOGY FOCUS, 2016, 2 (05): : 465 - 466
  • [24] Precision cancer medicine program for whole-exome sequencing of metastatic tumors reveals biomarkers of response
    Beltran, Himisha
    Eng, Kenneth
    Mosquera, Juan Miguel
    Sigaras, Alexandros
    Romanel, Alessandro
    Rennart, Hanna
    Kossai, Myriam
    Pauli, Chantal
    Faltas, Bishoy
    Fontugne, Jacqueline
    Robinson, Brian
    Nanus, David M.
    Tagawa, Scott T.
    Xiang, Jenny Z.
    Demichelis, Francesca
    Rickman, David
    Sboner, Andrea
    Elemento, Olivier
    Rubin, Mark A.
    [J]. CANCER RESEARCH, 2015, 75
  • [25] Precision Cancer Medicine Program for Whole Exome Sequencing (WES) of Metastatic Tumors Reveals Biomarkers of Response
    Mosquera, Juan Miguel
    Beltran, Himisha
    Sbonei, Andrea
    Kossai, Myriam
    Fontugne, Jacqueline
    Pauli, Chantal
    Park, Kyung
    Robinson, Brian
    Elemento, Olivier
    Rubin, Mark
    [J]. MODERN PATHOLOGY, 2015, 28 : 461A - 461A
  • [26] Precision Cancer Medicine Program for Whole Exome Sequencing (WES) of Metastatic Tumors Reveals Biomarkers of Response
    Mosquera, Juan Miguel
    Beltran, Himisha
    Sboner, Andrea
    Kossai, Myriam
    Fontugne, Jacqueline
    Pauli, Chantal
    Park, Kyung
    Robinson, Brian
    Elemento, Olivier
    Rubin, Mark
    [J]. LABORATORY INVESTIGATION, 2015, 95 : 461A - 461A
  • [27] Dancing with the DNA damage response: next-generation anti-cancer therapeutic strategies
    Minchom, Anna
    Aversa, Caterina
    Lopez, Juanita
    [J]. THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY, 2018, 10
  • [28] Genomic, Transcriptomic, and Functional Alterations in DNA Damage Response Pathways as Putative Biomarkers of Chemotherapy Response in Ovarian Cancer
    Sharma Saha, Sweta
    Gentles, Lucy
    Bradbury, Alice
    Brecht, Dominik
    Robinson, Rebecca
    O'Donnell, Rachel
    Curtin, Nicola J.
    Drew, Yvette
    [J]. CANCERS, 2021, 13 (06) : 1 - 17
  • [29] Comet assay measures of DNA damage as biomarkers of irinotecan response in colorectal cancer invitro and invivo
    Wood, Joanna P.
    Smith, Andrew J. O.
    Bowman, Karen J.
    Thomas, Anne L.
    Jones, George D. D.
    [J]. CANCER MEDICINE, 2015, 4 (09): : 1309 - 1321
  • [30] Cancer Genetic Markers According to Radiotherapeutic Response in Patients with Glioblastoma - Radiogenomic Approach for Precision Medicine
    Yang, K.
    Jung, S. W.
    Shin, H. M.
    Lim, D. H.
    Nam, D. H.
    Kim, S. T.
    [J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2018, 102 (03): : E376 - E377
12345