SPAK is part of the CD46-mediated signaling pathway that induces IL-10 production and T-regulatory cell development in human CD4+T-cells

被引：0
|
作者：
Kemper, C [1 ]
Caudy, A [1 ]
Price, J [1 ]
Atkinson, J [1 ]
机构：
[1] Univ Cardiff Wales, Dept Med Biochem & Immunol, Sch Med, Cardiff, Wales
来源：
MOLECULAR IMMUNOLOGY | 2006年 / 43卷 / 1-2期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
67
引用
收藏
页码：146 / 146
页数：1
相关论文
共 50 条
  • [21] CD46/CD3 activation of human CD4+ T lymphocytes induces a T-regulatory 1 (Tr1) phenotype
    Kemper, C
    Chan, AC
    Green, JM
    Brett, KA
    Murphy, KM
    Atkinson, JP
    FASEB JOURNAL, 2003, 17 (07): : C216 - C216
  • [22] Production of IL-10 by CD4+ regulatory T cells during the resolution of infection promotes the maturation of memory CD8+ T cells
    Brian J Laidlaw
    Weiguo Cui
    Robert A Amezquita
    Simon M Gray
    Tianxia Guan
    Yisi Lu
    Yasushi Kobayashi
    Richard A Flavell
    Steven H Kleinstein
    Joe Craft
    Susan M Kaech
    Nature Immunology, 2015, 16 : 871 - 879
  • [23] Production of IL-10 by CD4+ regulatory T cells during the resolution of infection promotes the maturation of memory CD8+ T cells
    Laidlaw, Brian J.
    Cui, Weiguo
    Amezquita, Robert A.
    Gray, Simon M.
    Guan, Tianxia
    Lu, Yisi
    Kobayashi, Yasushi
    Flavell, Richard A.
    Kleinstein, Steven H.
    Craft, Joe
    Kaech, Susan M.
    NATURE IMMUNOLOGY, 2015, 16 (08) : 871 - +
  • [24] CD4+T-cells are the predominant IL-10 producing cells in the circulation of filarial-infected patients
    Mitre, Edward
    Nutman, Thomas B.
    AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2005, 73 (06): : 202 - 202
  • [25] CD46-mediated costimulation induces a Th1-biased response and enhances early TCR/CD3 signaling in human CD4+ T lymphocytes
    Sánchez, A
    Feito, MJ
    Rojo, JM
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2004, 34 (09) : 2439 - 2448
  • [26] Inhibitory effect of IL-10 on T cells by altering the CD28 signaling pathway
    Fanny Monneaux
    Arthritis Research & Therapy, 3 (1)
  • [27] CD25+CD4+ T cells compete with naive CD4+ T cells for IL-2 and exploit it for the induction of IL-10 production
    Barthlott, T
    Moncrieffe, H
    Veldhoen, M
    Atkins, CJ
    Christensen, J
    O'Garra, A
    Stockinger, B
    INTERNATIONAL IMMUNOLOGY, 2005, 17 (03) : 279 - 288
  • [28] CD25+ CD4+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10
    Annacker, O
    Pimenta-Araujo, R
    Burlen-Defranoux, O
    Barbosa, TC
    Cumano, A
    Bandeira, A
    JOURNAL OF IMMUNOLOGY, 2001, 166 (05): : 3008 - 3018
  • [29] Oral IL-10 suppresses colon carcinogenesis via elimination of pathogenic CD4+T-cells and induction of antitumor CD8+T-cell activity
    Gu, Tao
    DeJesus, Magdia
    Burris, Thomas P.
    Egilmez, Nejat K.
    CANCER RESEARCH, 2017, 77
  • [30] Alterations in CD46-mediated Tr1 regulatory T cells in patients with multiple sclerosis
    Astier, Anne L.
    Meiffren, Gregory
    Freeman, Samuel
    Hafler, David A.
    JOURNAL OF CLINICAL INVESTIGATION, 2006, 116 (12): : 3252 - 3257
12345