Peptide-Based Multifunctional Nanomaterials for Tumor Imaging and Therapy

被引:118
|
作者
Zhang, Chi [1 ,2 ]
Wu, Wei [1 ,2 ]
Li, Run-Qing [1 ,2 ]
Qiu, Wen-Xiu [1 ,2 ]
Zhuang, Ze-Nan [1 ,2 ]
Cheng, Si-Xue [1 ,2 ]
Zhang, Xian-Zheng [1 ,2 ,3 ]
机构
[1] Wuhan Univ, Key Lab Biomed Polymers, Minist Educ, Wuhan 430072, Hubei, Peoples R China
[2] Wuhan Univ, Dept Chem, Wuhan 430072, Hubei, Peoples R China
[3] Wuhan Univ, Inst Adv Studies, Wuhan 430072, Hubei, Peoples R China
基金
中国国家自然科学基金;
关键词
nanomedicine; peptides; tumor imaging; tumor therapy; FIBROBLAST ACTIVATION PROTEIN; AGGREGATION-INDUCED EMISSION; TARGETED CHIMERIC PEPTIDE; HOST-DEFENSE PEPTIDES; DRUG-DELIVERY SYSTEM; EXTRACELLULAR-MATRIX; PHOTODYNAMIC THERAPY; FLUORESCENT-PROBE; CYSTEINE CATHEPSINS; ANTICANCER ACTIVITY;
D O I
10.1002/adfm.201804492
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
During the last decade, peptide-based nanomaterials are recognized as upcoming biomedical materials for tumor imaging and therapy. The rapid expansion of peptides and peptide derivatives is almost owing to their excellent biocompatibility, diverse bioactivity, potentia biodegradability, specific biological recognition ability, and easy chemical modification characteristic. The present review outlines the development up to now concerning the design and biomedical applications of peptide-based multifunctional nanomaterials, with an emphasis on their variegated therapeutic methods.
引用
收藏
页数:22
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