[1] Univ Toronto, Interdept Div Crit Care Med, Toronto, ON, Canada
[2] St Michaels Hosp, Keenan Res Ctr, Toronto, ON, Canada
[3] St Michaels Hosp, Li Ka Shing Knowledge Inst, Dept Crit Care, Toronto, ON, Canada
[4] Peking Univ, Dept Crit Care Med, Hosp 3, Beijing 100191, Peoples R China