A New Monoterpenoid and a New Flavonoid Glycoside from the Peels of Clausena lansium

被引：0
|
作者：
Deng, Hui-Dong [1 ,2 ,3 ]
Cai, Cai-Hong [2 ]
Liu, Shuai [2 ]
Zeng, Yan-Bo [2 ]
Mei, Wen-Li [2 ]
He, Fan [3 ]
Hua, Min [3 ]
Dai, Hao-Fu [2 ]
Li, Shao-Peng [1 ]
机构：
[1] Hainan Univ, Minist Educ, Hort & Garden Coll, Key Lab Protect & Dev Utilizat Trop Crop Germplas, Haikou 570228, Peoples R China
[2] Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Minist Agr, Key Lab Biol & Genet Resources Trop Crops, Haikou 571101, Peoples R China
[3] Hainan Acad Agr Sci, Inst Trop Fruit Tree, Haikou 571100, Peoples R China
来源：
NATURAL PRODUCT COMMUNICATIONS | 2016年 / 11卷 / 05期
关键词：
Clausena lansium; Monoterpenoid; Flavonoid; Antibacterial activity; Hypoglycemic activity; ALKALOIDS; AMIDE; SEEDS;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
One new monoterpenoid, nerol oxide-8-carboxylic acid (1), and one new flavonoid glycoside, claulansoside A (2), together with six known compounds, clausenamide (3), quercetin (4), isorhamnetin (5), dihydromyric (6), 2 '',3 ''-dihydroxyanisolactone (7) and (E,E)-8-(7-hydroxy-3,7-dimethylocta-2,5-dienyloxy)psoralen (8), have been isolated from the peels of Clausena lansiunz (Lour.) Skeels. Their structures were determined using a combination of ID, and 2D NMR (HMQC, HMBC, COSY and NOESY) techniques, and HR-ESI-MS analyses. Compounds 1 and 7 exhibited antibacterial activity against Staphylococcus aureus with the diameter of inhibition zones of 11.5 mm and 14.2 mm. Compounds 3 and 6 showed a-glucosidase inhibitory activity in vitro.
引用
收藏
页码：573 / 575
页数：3
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