Lovastatin production by Aspergillus terreus in solid-state fermentation

被引：36
|
作者：
Wei, Pei-lian [1 ]
Xu, Zhi-nan
Cen, Pei-lin
机构：
[1] Zhejiang Univ, Inst Biochem Engn, Dept Chem Engn & Bioengn, Hangzhou 310027, Peoples R China
[2] Zhejiang Univ, Dept Biochem Engn, Hangzhou 310023, Peoples R China
来源：
JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE A | 2007年 / 8卷 / 09期
关键词：
solid-state fermentation (SSF); rice; lovastatin; Aspergillus terreus;
D O I：
10.1631/jzus.2007.A1521
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Lovastatin production by Aspergillus terreus ATCC 20542 in solid-state fermentation (SSF) was studied. Various substrates were used to evaluate the ability of A. terreus to produce lovastatin. The results showed that either rice or wheat bran was suitable substrate for lovastatin production in SSF. The maximum yield of lovastatin (2.9 mg/g dry substrate) using rice as substrate was achieved after incubating for 11 d at the following optimized process parameters: 50%similar to 60% initial moisture content, pH 5.5, incubation temperature 28 degrees C.
引用
收藏
页码：1521 / 1526
页数：6
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