Granzyme B Proteolyzes Thrombospondin-1 in RPE Cells and Choroidal Neovascularization

被引:0
|
作者
Obasanmi, Gideon [1 ]
Zeglinski, Matthew R. [2 ]
Tian, Erika Yuan [1 ]
To, Eleanor [1 ]
Cui, Jing Z. [1 ]
Granville, David [2 ]
Matsubara, Joanne A. [1 ]
机构
[1] Univ British Columbia, Ophthalmol & Visual Sci, Fac Med, Vancouver, BC, Canada
[2] Univ British Columbia, Dept Pathol, Fac Med, Vancouver, BC, Canada
基金
加拿大健康研究院; 加拿大自然科学与工程研究理事会;
关键词
D O I
暂无
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
473
引用
收藏
页数:3
相关论文
共 50 条
  • [11] Disruption of thrombospondin-2, but not thrombospondin-1, accelerates neovascularization in murine hindlimb ischemia
    Kalka, C
    Silver, M
    Lawler, J
    Kyriakides, TR
    Bornstein, P
    CIRCULATION, 2001, 104 (17) : 33 - 33
  • [12] Thrombospondin-1 localization in human retina and choroidal neovascular membranes
    He, S
    Hofman, F
    Lopez, P
    Ryan, SJ
    Hinton, DR
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 1997, 38 (04) : 1646 - 1646
  • [13] Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1
    Benilde Jiménez
    Olga V. Volpert
    Susan E. Crawford
    Maria Febbraio
    Roy L. Silverstein
    Noël Bouck
    Nature Medicine, 2000, 6 : 41 - 48
  • [14] Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1
    Jiménez, B
    Volpert, OV
    Crawford, SE
    Febbraio, M
    Silverstein, RL
    Bouck, N
    NATURE MEDICINE, 2000, 6 (01) : 41 - 48
  • [15] The role of thrombospondin-1 in RPE migration and in human RPE-induced collagen matrix contraction.
    Sheridan, CM
    Hiscott, P
    Grierson, I
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2001, 42 (04) : S811 - S811
  • [16] Positive stimulation by retinoic acid on production of thrombospondin-1 (TSP-1) in human retinal pigment epithelial (RPE) cells
    Uchida, HM
    Hayashi, H
    Oshima, K
    Beppu, R
    Kuroki, M
    Kuroki, M
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 1999, 40 (04) : S926 - S926
  • [17] Thrombospondin-1 blocks redox signaling in vascular cells
    Isenberg, J. S.
    Wink, D. A.
    Roberts, D. D.
    MATRIX BIOLOGY, 2006, 25 : S55 - S55
  • [18] THROMBOSPONDIN-1 KNOCKOUT MICE SHOW DELAYED ORGANIZATION AND PROLONGED NEOVASCULARIZATION OF SKIN WOUNDS
    POLVERINI, PJ
    DIPIETRO, LA
    DIXIT, VM
    HYNES, RO
    LAWLER, J
    FASEB JOURNAL, 1995, 9 (03): : A272 - A272
  • [19] The role of matricellular proteins thrombospondin-1 and osteonectin during RPE cell migration in proliferative vitreoretinopathy
    Sheridan, CM
    Magee, RM
    Hiscott, PS
    Hagan, S
    Wong, DH
    McGalliard, JN
    Grierson, I
    CURRENT EYE RESEARCH, 2002, 25 (05) : 279 - 285
  • [20] Monocyte/macrophages promote vasculogenesis in choroidal neovascularization in mice by stimulating SDF-1 expression in RPE cells
    Yuan-yuan Shi
    Yu-sheng Wang
    Zhao-xia Zhang
    Yan Cai
    Jing Zhou
    Hui-yuan Hou
    Nico van Rooijen
    Graefe's Archive for Clinical and Experimental Ophthalmology, 2011, 249 : 1667 - 1679