Studies of reservoir hosts for Marburg virus

被引:182
|
作者
Swanepoel, Robert [1 ]
Smit, Sheilagh B.
Rollin, Pierre E.
Formenty, Pierre
Leman, Patricia A.
Kemp, Alan
Burt, Felicity J.
Grobbelaar, Antoinette A.
Croft, Janice
Bausch, Daniel G.
Zeller, Herve
Leirs, Herwig
Braack, L. E. O.
Libande, Modeste L.
Zaki, Sherif
Nichol, Stuart T.
Kslazek, Thomas G.
Paweska, Janusz T.
机构
[1] Natl Inst Communicable Dis, Private Bag X4, ZA-2131 Johannesburg, South Africa
[2] Ctr Dis Control & Prevent, Atlanta, GA USA
[3] WHO, CH-1211 Geneva, Switzerland
[4] Univ Free State, Bloemfontein, South Africa
[5] Tulane Sch Publ Hlth & Trop Med, New Orleans, LA USA
[6] Inst Pasteur, Lyon, France
[7] Univ Antwerp, B-2020 Antwerp, Belgium
[8] Univ Aarhus, Lyngby, Denmark
[9] Conservat Int, Cape Town, South Africa
[10] Dept Hlth, Watsa, DEM REP CONGO
关键词
D O I
10.3201/eid1312.071115
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
To determine reservoir hosts for Marburg virus (MARV), we examined the fauna of a mine in northeastern Democratic Republic of the Congo. The mine was associated with a protracted outbreak of Marburg hemorrhagic fever during 1998-2000. We found MARV nucleic acid in 12 bats, comprising 3.0%-3.6% of 2 species of insectivorous bat and 1 species of fruit bat. We found antibody to the virus in the serum of 9.7% of 1 of the insectivorous species and in 20.5% of the fruit bat species, but attempts to isolate virus were unsuccessful.
引用
收藏
页码:1847 / 1851
页数:5
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