Efficient asymmetric addition of diethylzinc to ketones using tartaric acid derivative as chiral ligand

被引：5

作者：

Hui, Ailing ^{[2
]}

Zhang, Jintang ^{[1
]}

Sun, Huayin ^{[1
]}

Wang, Zhiyong ^{[1
]}

机构：

[1] Univ Sci & Technol China, Dept Chem, 96 Jinzhai Rd, Anhua 230026, Peoples R China

[2] Hefei Univ Technol, Minist Educ, Engn Res Ctr Bioproc, Hefei 230009, Anhui, Peoples R China

来源：

ARKIVOC | 2008年

关键词：

tartaric acid; asymmetric addition; diethylzinc; aldehyde; ketone;

D O I：

10.3998/ark.5550190.0009.204

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new chiral ligand derived from natural tartaric acid was synthesized and was applied to the asymmetric addition of diethylzinc to aldehyde and ketones. Moderate to good enantioselectivities were obtained in the asymmetric addition of diethylzinc to ketones with 10% mol catalyst loading at room temperature.

引用

页码：25 / 32

页数：8

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