Sjogren Syndrome in Primary Salivary Gland Lymphoma A Systematic Review and Meta-Analysis

被引:1
|
作者
Travaglino, Antonio [1 ]
Giordano, Claudia [2 ]
Pace, Mirella [1 ]
Varricchio, Silvia [1 ]
Picardi, Marco [2 ]
Pane, Fabrizio [2 ]
Staibano, Stefania [1 ]
Mascolo, Massimo [1 ]
机构
[1] Federico II Univ Naples, Pathol Sect, Dept Adv Biomed Sci, Naples, Italy
[2] Federico II Univ Naples, Hematol Sect, Dept Clin Med & Surg, Naples, Italy
关键词
Salivary gland; Lymphoma; MALT; Sjogren; Parotid; MARGINAL ZONE LYMPHOMA; NON-HODGKINS-LYMPHOMAS; TISSUE LYMPHOMA; MALT LYMPHOMA; DIAGNOSIS; TUMOR; NECK; HEAD;
D O I
10.1093/AJCP/AQAA005
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Objectives: Sjogren syndrome (SS) is considered as a major etiologic factor for primary salivary gland lymphoma (SGL). However, the percentage of SGL that is caused by SS (and thus the real impact of SS on SGL epidemiology) is unclear. We aimed to assess the prevalence of SS in patients with SGL through a systematic review and meta-analysis. Methods: Electronic databases were searched for studies assessing the presence of SS in patients with SGL. Pooled prevalence of SS in SGL was calculated, with a subgroup analysis based on histotype (mucosa-associated lymphoid tissue [MALT] vs non-MALT). Results: Sixteen studies with 665 SGLs were included. Pooled prevalence of SS in SGL was 18.2%, with high heterogeneity among studies. In MALT SGL, the prevalence of SS was 29.5%, with moderate heterogeneity. In non-MALT SGL, the prevalence of SS was 0%, with null heterogeneity. Conclusions: SS seems to be responsible for a significant but minor portion of SGLs. SS appears involved in MALT-type SGL but not in other histotypes.
引用
收藏
页码:719 / 724
页数:6
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